The presence of clay soil causes problems at the base structure: it swells when wet and shrinks dry, which provides a reduction in resistance to cutting soil. Plastic waste form polyamide powder (PA-12) from 3D printing industry can be used improve mechanical properties This experimental study is an attempt combine these two objectives stabilizing by using PA-12. shear resistant gave us confide...

Experimental studies have been carried out to study the effect of various fillers on physicomechanical and tribotechnical properties compositions, optimal filler contents established, which ensure best polyethylene, polypropylene, polystyrol polyamide structural composite materials. The principle design shock-resistant, antifriction antifriction-wear-resistant materials is proposed. Highly effi...

We recently developed a new type of pyrrole (Py)-imidazole (Im) polyamide-tetrahydrocyclopropabenzindolone (CBI) conjugate with an indole linker as a stable sequence-specific alkylating agent. In this study, we investigated the gene silencing activities of polyamides A, B and C, which selectively alkylate specific sequences in the promoter region, non-coding strand and coding strand, respective...

This research investigated the direct bonding mechanism of dissimilar materials such as metals and plastic by the conventional hot pressing process. The press area of 4 x 4 mm2 was used for direct bonding. The results of the study showed that titanium was completely bonded to polyamide 66. On the other hand, titanium was not bonded to polystyrene. In the case of bonding material of titanium wit...

In this study, the mechanical performances of neat Polyamide 6 (PA6) polymer, 20wt.% glass fiber reinforced PA6, and 8% SEBS elastomer with 20% PA6 composite were investigated. Composite materials first produced in form granules by using a twin-screw extruder. Later, test samples molded, accordance American Society Testing Materials (ASTM) standards, an injection molding technique. Mechanical p...

Vascular endothelial growth factor (VEGF) and its receptors have been implicated as key factors in tumor angiogenesis that are up-regulated by hypoxia. We evaluated the effects of DNA-binding small molecules on hypoxia-inducible transcription of VEGF. A synthetic pyrrole-imidazole polyamide designed to bind the hypoxia response element (HRE) was found to disrupt hypoxia-inducible factor (HIF) b...

Pyrrole-imidazole (Py-Im) polyamides are high affinity DNA-binding small molecules that can inhibit protein-DNA interactions. In VCaP cells, a human prostate cancer cell line overexpressing both AR and the TMPRSS2-ERG gene fusion, an androgen response element (ARE)-targeted Py-Im polyamide significantly downregulates AR driven gene expression. Polyamide exposure to VCaP cells reduced proliferat...

Based on a previously developed polyamide proton conductive macromolecule, the nano-scale structure of the self-assembled proton conductive channels (PCCs) is adjusted via enlarging the nano-scale pore size within the macromolecules. Hyperbranched polyamide macromolecules with different size are synthesized from different monomers to tune the nano-scale pore size within the macromolecules, and ...

All-polyamide composite coated-fabric (APCCF) was used as an alternative material for the construction of textile-bioreactors (TBRs), which are prepared as a replacement of the traditional stainless steel bioreactors (SSBRs) or concrete-based bioreactors. The material characteristics, as well as the fermentation process performance of the APCCF-TBR, was compared with a TBR made using the polyvi...