Anti-triiodothyronine antibody was found in a case of rheumatoid arthritis associated with Hashimoto's thyroiditis. The patient was a 40 year-old woman who had complained of polyarthralgia, joint-swelling and stiffness for seven years. She had a rheumatoid nodule and showed a positive RA test. Radiographic changes of hands and wrists showed osteoporosis, erosions and narrowing of joint space. N...

and interstitial lung disease is frequently identifi ed abnormality by CT. 3 Here we present a JDM case with severe heliotrope rash and uncommon manifestation in CT image of the lung. A 15-year-old girl presented with a 3-month history of progressive periorbital swelling and a reddishpurple rash on the upper and lower eyelids ( fi gure 1A ). Her vision acuity decreased and MRI showed only thick...

Case report A 63 year old lady presented to a peripheral centre polyarthralgia, multiple tender and erythematous nodules over her face, elbows, back and legs and continuous fever of 2 months duration. Routine investigations being negative, she was referred for further evaluation of PUO. On presentation, the patient was febrile. Apart from the nodules, examination revealed bilaterally thickened ...

BACKGROUND Arthritogenic alphaviruses, including Chikungunya virus (CHIKV), are responsible for acute fever and arthralgia, but can also lead to chronic symptoms. In 2006, a Chikungunya outbreak occurred in La Réunion Island, during which we constituted a prospective cohort of viremic patients (n = 180) and defined the clinical and biological features of acute infection. Individuals were follow...

Septic arthritis caused by N gonorrhoeae is monoarticular or pauciarticular, and is more commonly associated with positive synovial fluid cultures and negative blood cultures. Gonococcal bacteremia is more likely to be associated with polyarthralgias and skin lesions. The diagnosis of gonococcal arthritis or DGI is also secure if a mucosal gonococcal infection is documented in the presence of a...

Polyarthritis is a frequent presenting symptom in patients with sarcoidosis (Scadding, 1956; James, 1956). It is especially common in association with erythema nodosum; the combination of polyarthritis, erythema nodosum, and bilateral hilar adenopathy forming one of the distinctive syndromes of this disease (LUfgren, 1953; James, Thomson, and Willcox, 1956). Thus, Lofgren, in his series of 212 ...

C hikungunya virus (CHIKV) is an alphavirus transmitted in an urban epidemic cycle by the mosquitoes Aedes aegypti and Ae. albopictus. CHIKV outbreaks are characterized by rapid spread and infection rates as high as 75%; 72%–93% of infected persons become symptomatic. The disease manifests as acute fever and potentially de-bilitating polyarthralgia. In a variable proportion of cases, polyarthri...

Large outbreaks of chikungunya fever can occur when chikungunya virus (CHIKV) is introduced into a susceptible population where the appropriate vectors are present (1). It has been long known that many countries located within the Carribean have conditions appropriate to support a CHIKV outbreak (2). On December 7, 2013, the World Health Organization reported the first local autochthonous trans...

The case of a 45 year old woman presenting with fever of unknown origin, headache, polyarthralgia, and chest pain is described. Computed tomography scans and angiography disclosed a mediastinal tumour with a complete obstruction of the right pulmonary artery, positron emission tomography scans showed a tracer accumulation in the walls of the pulmonary artery and the aorta. Thoracotomy was perfo...

T he belief that a genetic susceptibility to the development of sarcoidosis exists is supported by several lines of evidence: 1) monozygotic twins are more often concordant for the disease than dizygotic twins; 2) sarcoidosis patients are more likely than healthy subjects to report a sibling or parent affected with the disease; 3) prevalence, incidence and severity of sarcoidosis vary widely am...