Polyethylene glycol (PEG) is a biocompatible polymer that is often attached to therapeutic molecules to improve bioavailability and therapeutic efficacy. Although antibodies with specificity for PEG may compromise the safety and effectiveness of PEGylated medicines, the prevalence of pre-existing anti-PEG antibodies in healthy individuals is unclear. Chimeric human anti-PEG antibody standards w...

Excellent strength regenerated alginate composite fibers mixed with Poly (ethylene glycol) grafted cellulose nanocrystals (CNC-g-PEG) were prepared through a simple and scalable blending strategy. Firstly, high modulus (CNCs) fabricated based on waste cotton fabrics by the chemical treatment. (PEG) different molecular weight was onto CNC surface. The from CNC-g-PEG/sodium spinning dope wet spin...

Biodegradable macromolecular Gd(III) complexes, Gd-DTPA cystine copolymers (GDCP), were grafted with PEG of different sizes to modify the physicochemical properties and in vivo MRI contrast enhancement of the agents and to study the effect of PEG chain length on these properties. Three new PEG-grafted biodegradable macromolecular gadolinium(III) complexes were synthesized and characterized as b...

With growing concern for potential negative impacts to health or the environment of new types consumer goods reaching market, a major challenge both policy makers and producers is understand conditions uptake innovation in situation uncertainty concerning risk related these products. Our contribution studies effects economic growth production scientific knowledge on risk, uptake. It focuses cas...

A modi®ed two stage in vitro digestion method was used to study the effects of rate of PEG addition (0±1100 mg/g DM) on dry matter (IVDMD) and nitrogen digestibility (IVND) of freeze dried leaf materialfromactivelygrowingshootsofCalliandracalothyrsus (Calliandra)andLeucaenaleucocephala cv. Cunningham (Leucaena). For both species, IVDMD and IVND increased asymptotically with PEG rate; the IVND r...

An 84-year-old woman with vascular dementia and percutaneous endoscopic gastrostomy (PEG) placement 2 months prior presented with a fecal odor from the PEG tube and diarrhea at each feeding. No feces output from the PEG tube or peristomal leakage was noted. Computed tomography of the abdomen showed penetration of the PEG tube through the transverse colon to the stomach, without surrounding infl...

A simple method was developed to fabricate polyethylene glycol (PEG) nanostructures using capillary lithography mediated by ultraviolet (UV) exposure. Acrylate-containing PEG monomers, such as PEG dimethacrylate (PEG-DMA, MW = 330), were photo-cross-linked under UV exposure to generate patterned structures. In comparison to unpatterned PEG films, hydrophobicity of PEG nanostructure modified sur...