Frontispiece: In article number 2100063 by Patrick Theato, Hatice Mutlu, and Edgar Molle, a set of novel poly(N-(4-vinylphenyl)sulfonamide) s featuring varying electron densities is prepared in straightforward fashion subsequently used post-polymerization modification reactions via aza-Michael addition with different electron-defi cient alkenes as Michael acceptors for the facile synthesis poly...

Evidence from a variety of spectroscopic probes indicates that (phi, psi) values corresponding to the left-handed polyproline II helix (P(II)) are preferred for short alanine-based peptides in water. On the basis of results from theoretical studies, it is believed that the observed preference is dictated by favorable peptide-solvent interactions, which are realized through formation of optimal ...

The isolation of trimethoprim-resistant, sulfonamide-susceptible Enterobacteriaceae causing urinary tract infections is reported. The appearance of these strains followed the introduction of trimethoprim alone for use as treatment. Trimethoprim resistance was attributable to plasmids or transposons less frequently in sulfonamide-susceptible Escherichia coli isolates than in sulfonamide-resistan...