نتایج جستجو برای: port wine stains
تعداد نتایج: 51497 فیلتر نتایج به سال:
BACKGROUND The prevalence of capillary malformations, also known as port-wine stains (PWS), is 0.3%. Familial segregation can occur. The capillary malformation-arteriovenous malformation (CM-AVM) phenotype is caused by mutations in the RASA1 gene. In PWS familial cases, the inheritance is considered to be autosomal dominant with variable penetrance. OBJECTIVE Investigation of the heredity of ...
BACKGROUND AND OBJECTIVES Neither the pathogenesis of port wine stain (PWS) birthmarks nor tissue effects of pulsed dye laser (PDL) treatment of these lesions is fully understood. There are few published reports utilizing gene expression analysis in human PWS skin. We aim to compare gene expression in PWS before and after PDL, using DNA microarrays that represent most, if not all, human genes t...
Port-wine stains (PWS) are congenital capillary malformations, usually occurring on the face, neck, and other exposed parts of the skin, that have serious psychological and social impact on the patient. Most researchers focus on the treatment of PWS, but the quality of life (QoL) of PWS patients is seldom researched. The objective of this study is to evaluate the QoL of patients with PWS on exp...
OBJECTIVE The purpose of this clinical study was to evaluate the efficacy of an intense pulsed light (IPL) irradiator system for the treatment of port-wine stains (PWS) resistant to multiple pulsed dye laser (PDL) treatments. MATERIALS AND METHODS Fifteen PWS patients, who were previously found to be resistant to multiple PDL treatments, were treated four times with a second generation IPL sy...
BACKGROUND Port-wine stains (PWS) affect 0.3% to 0.5% of newborns and pulsed dye laser (PDL) remains the treatment of choice. Optimal treatment intervals have not been established. OBJECTIVE We sought to validate the optimal treatment intervals for the management of facial PWS with PDL. METHODS In all, 24 infants with facial PWS who received at least 5 treatments with the PDL at 2-, 3-, and...
BACKGROUND Port wine stains (PWS) affect 0.3-0.5% of both sexes of newborns, usually occurring on the face. OBJECTIVE To document safety and effectiveness of cryogen spray cooled, pulsed-dye laser at higher fluences than previously used to lighten facial PWS in infants < or =6 months, and establish that frequent treatment early in life yields better clearance than if delayed until later in li...
From the Biochemistry, Cellular and Molecular Biology Program (M.D.S., J.D.B., J.P.) and the Departments of Dermatology (B.C.), Neurology (A.M.C.), Pediatrics (A.M.C.), and Psychiatry and Behavioral Sciences (J.P.), Johns Hopkins School of Medicine, and the Department of Neurology and Developmental Medicine, Hugo W. Moser Research Institute at Kennedy Krieger (M.D.S., J.D.B., L.P.F., A.M.C., J....
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