The antimicrobial activity of copaiba oils was tested against Gram-positive and Gram-negative bacteria, yeast, and dermatophytes. Oils obtained from Copaifera martii, Copaifera officinalis, and Copaifera reticulata (collected in the state of Acre) were active against Gram-positive species (Staphylococcus aureus, methicillin-resistant S. aureus, Staphylococcus epidermidis, Bacillus subtilis, and...

Cefatrizine, a new oral semisynthetic cephalosporin, was evaluated in vitro and in the treatment of 18 patients with acute urinary tract infection, pneumonia, and soft tissue infection. In vitro, it was more active than cephalexin for gram-positive and gram-negative bacteria. It was also more active than cephalothin, cefazolin, and cephapirin against most of the gram-negative bacteria but less ...

The present study was aimed to evaluate the antibacterial activity of Amorphophallus campanulatus (family: Araceae) commonly known as jangli suran. The root, stem and leaf of A. campanulatus, extracted successively with polar (aqueous, methanol), dipolar (acetone) and non polar (chloroform) solvents, yielded more phyto compounds in case of root followed by stem and leaf. The extracts were asses...

Aqueous extracts and organic solvent extracts of isolated marine cyanobacteria strains were tested for antimicrobial activity against a fungus, Gram-positive and Gram-negative bacteria and for cytotoxic activity against primary rat hepatocytes and HL-60 cells. Antimicrobial activity was based on the agar diffusion assay. Cytotoxic activity was measured by apoptotic cell death scored by cell sur...

BACKGROUND Clausena anisata belongs to the family Rutaceae, a shrub widely used in West Africa for the treatment of bacterial and fungal infections of the skin including boils, ringworm and eczema. The study was designed to evaluate the antimicrobial activity and phytochemical screening of ethanol leaf extract of C. anisata (CLE). METHOD Antimicrobial activity of CLE was investigated using ag...

In this study heterocyclic compounds were prepared from thioxanthone derivatives and determined their structure by measuring melting point (M.P) infrared spectrum (FTR) 1HNMR for each one. These used testing antibacterial activity Streptococcus mutans, Staphylococcus saprophyticus, Enterococcus faecalis (Gram positive bacteria) Haemophilus influenzae negative bacteria). Prepared I,II,III,IIV sh...

Infections with gram-positive bacteria are a major cause of morbidity and mortality in humans. Opsonin-dependent phagocytosis plays a major role in protection against and recovery from gram-positive infections. Inborn and acquired defects in opsonin generation and/or recognition by phagocytes are associated with an increased susceptibility to bacterial infections. In contrast, the physiological...

The in vitro antimicrobial activity of the essential oil isolated from the aerial parts of Cymbopogon Olivieri (Boiss.) Bor, an aromatic grass of Iran was tested against three Gram-negative and four Gram-positive bacteria and also three fungi. The results of the bioassays showed that the oil has a remarkable antimicrobial activity. Bacillus subtilis and Candida albicans were more sensitive to t...

wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. deoxyvasicinone which wa...