Backgrounds: Neutropenia can be associated with life-threatening infections. Gram negative and staphylococcal infections are the most common pathogens. The spectrum of bacterial isolates has changed considerably over the past four decades. The objective of the present study was to evaluate the pattern of bacterial and fungal infections in neutropenic pediatric patients. Methods: A non-randomize...

BACKGROUND Myxoma resistance protein 1 (MxA) is induced during viral infections. MxA testing could be helpful to differentiate between viral and bacterial infections. METHODS A prospective multicenter cohort study was performed in pediatric emergency departments. MxA blood values were measured in children with confirmed viral or bacterial infections, uninfected controls, and infections of unk...

BACKGROUND External ocular infection is a public health problem in Ethiopia. The aim of this study was to determine the prevalence and antimicrobial susceptibility pattern of external ocular bacterial infections. METHODS A cross sectional study was conducted at the University of Gondar Hospital among patients seeking health services at the Department of Ophthalmology from January to April, 20...

BACKGROUND Traditional imaging techniques for the localization and monitoring of bacterial infections, although reasonably sensitive, suffer from a lack of specificity. This is particularly true for musculoskeletal infections. Bacteria possess a thymidine kinase (TK) whose substrate specificity is distinct from that of the major human TK. The substrate specificity difference has been exploited ...

We have reviewed the incidence, type and site of microbiologically proven bacterial infection occurring in 52 patients with the acquired immunodeficiency syndrome (AIDS) who presented to Southmead Hospital, Bristol between 1990 and 1994. A total of 30 (58%) patients had significant bacterial isolates. The majority of infections were community acquired. Overall, more infections were caused by Gr...

BACKGROUND Bacteria are the major contributor of ocular infections worldwide. Ocular infections, if left untreated, can damage the structures of the eye with possible blindness and visual impairments. This work was aimed to review the bacterial profile of ocular infections. METHODS Literature search was made in different electronic databases; the review was systematically made to get concrete...

Our aim was to investigate whether serum neopterin and beta 2-microglobulin have any value in the distinction between Pneumocystis carinii pneumonia (PCP) and pneumonia due to extracellular bacteria. Also, to study whether neopterin and beta 2-microglobulin would correlate with the clinical course of lung infections in human immunodeficiency virus (HIV)-positive and HIV-negative patients. Thirt...

Neutropenia and risk of infectious complications It has been appreciated for 50 years that neutropenia predisposes patients to infectious diseases. The degree and duration of neutropenia predict the risk of infectious complications, and resolution of infections is linked to myeloid recovery (1). Chemotherapy-related oral and gastrointestinal mucositis play an important role in contributing to t...

backgrounds: neutropenia can be associated with life-threatening infections. gram negative and staphylococcal infections are the most common pathogens. the spectrum of bacterial isolates has changed considerably over the past four decades. the objective of the present study was to evaluate the pattern of bacterial and fungal infections in neutropenic pediatric patients.   methods: a non-randomi...