BACKGROUND Clonidine may be used along with intrathecal morphine for single-dose postoperative analgesia in adults. The efficacy of this is not clear. METHODS A meta-analysis was performed for two endpoints of efficacy: the time to first postoperative analgesia request and the amount of systemic morphine used during the first 24 h after operation. A Bayesian inference supporting direct statem...

Background: Different additive drugs such as opioids, epinephrine, clonidine, and neostigmine have been used along with local anaesthetics to improve the duration and quality of analgesia. Few studies have demonstrated the increase of efficacy in various aspects after combining dexmedetomidine and ropivacaine and dexmedetomidine to caudal bupivacaine in pediatric major abdominal cancer surgerie...

conclusions intra-articular levobupivacaine-tenoxicam-morphine combination provides effective pain relief, longer analgesic duration, and less analgesic requirement when compared with intra-articular levobupivacaine-tenoxicam-tramadol combination and saline after knee arthroscopic surgery. results vasr and vasa were significantly higher in group s in comparison to other groups (p < 0.05). durat...

Introduction Continuous interscalene nerve blockade (CISNB) has been shown to reduce postoperative pain and morphine usage after a wide range of shoulder operations (1&2). Recent trends to minimally invasive shoulder surgery are expected to be associated with shorter postoperative stays. This study compared the length of stay using CISNB as the primary postoperative analgesia with other forms o...

In a prospective randomized double blind clinical study, 120 patients of either sex in the age group of 25-65 years with ASA I and II, who were scheduled to undergo elective laparoscopic cholecystectomy were allocated to two groups of 60 patients each with regard to postoperative analgesia. In Group-I (n=60) the patients received Bupivacaine (0.5%) 20ml, instilled in gallbladder bed and the und...

To the best of our knowledge, the effect of pre-emptively blocking pain transmission on acute postoperative cognitive dysfunction (POCD) has not yet been assessed. Therefore, the present study aimed to investigate the effect of pre-emptive analgesia via a continuous femoral nerve block (CFNB) on postoperative pain and early cognitive function following total knee arthroplasty (TKA) surgery in e...

BACKGROUND AND GOAL OF STUDY After laparoscopic cholecystectomy, patients have moderate pain in the early postoperative period. Some studies shown beneficial effects of subcostal transversus abdominis plane block on reducing this pain. Our goal was to investigate influence of subcostal transversus abdominis plane block on postoperative pain scores and opioid consumption. MATERIALS AND METHODS...

BACKGROUND Parents have the right to decide on behalf of their children and deny consent to regional anaesthesia. The investigators decided to investigate quality of postoperative analgesia in adolescents undergoing epidural and opioid analgesia following the Nuss procedure. material/methods: The study subjects were 61 adolescents aged 11-18 years who underwent pectus excavatum repair with the ...

BACKGROUND In abdominal wall reconstruction, adequate pain control and minimization of narcotic consumption are essential to improving patient outcomes and satisfaction. Previous studies have examined the role of individual strategies, such as neuraxial analgesia and multimodal analgesia. However, there has not been a study that examined all potential determinants of postoperative narcotic requ...