OBJECTIVE Tranexamic acid (TA), a synthetic antifibrinolytic drug, has been shown to reduce postoperative bleeding and the need for allogeneic blood transfusion in cardiac surgery. However, the optimal dose regimen of TA is still under debate. The aim of this study was to evaluate whether a lower-dose TA regimen produced equivalent efficacy to its higher-dose counterpart in reducing postoperati...

The objective: to evaluate of postoperative complications, duration surgical intervention and hospital stay patients after hysteroscopic surgery using monopolar or bipolar electrodes.Materials methods. Eighty gynecological who had were divided into two groups 40 women each. Patients the I (main) group procedures a electrode, persons in II (comparison) – electrode. registration operative complic...

Abstract Patients undergoing cardiac surgery are at risk of excessive bleeding and its associated complications. Excessive during after has an incidence ~20%. Massive subsequent requirement for blood product administration mediastinal reexploration with significant morbidity mortality. Postoperative, nonsurgical in surgical patients is often multifactorial. Platelet dysfunction, fibrinolysis, h...

OBJECTIVE To analyze the preoperative plasma antigenic concentration and activity of von Willebrand factor and its main cleaving protease ADAMTS-13 in pediatric patients with cyanotic congenital heart disease undergoing surgical treatment and investigate possible correlations with postoperative bleeding. METHODS Plasma antigenic concentrations (von Willebrand factor:Ag and ADAMTS-13:Ag) were ...

OBJECTIVES The purpose of this multicentre cohort study was to examine the relationship between antiplatelet therapy (APT) at the time of coronary artery bypass grafting (CABG) and postoperative bleeding complications, transfusion requirements and adverse cardiovascular events. METHODS A matched-pair analysis was carried out on 6350 consecutive patients undergoing CABG at the three university...

Introduction: This study aimed to compare operation time, intraoperative bleeding and postoperative pain between cold dissection tonsillectomy and harmonic scalpel tonsillectomy. Materials and Methods: In this single-blinded clinical trial, 32 patients aged 14–48 were enrolled. Each patient randomly underwent tonsillectomy using the harmonic scalpel on one side and cold dissection on the other ...

RATIONALE Tracheostomy is done mostly in critically ill patients, many of whom may not survive. We still do not know the long term complications of tracheostomy itself; tracheal and subglottic stenosis, and tracheomalacia. OBJECTIVES To compare the complications of surgical tracheostomy (ST) versus percutaneous dilatational tracheostomy (PDT) by means of MRI control up to 1 month after closed...

BACKGROUND Haemorrhoidectomy is associated with complications including pain, bleeding and wound infection which can result prolonged hospital stay. Haemorrhoidectomy is considered to provide a better outcome in terms of postoperative pain and wound healing. Aims were to compare postoperative pain, bleeding, operating time and wound healing in patients undergoing open and closed haemorrhoidecto...

We retrospectively evaluated the effects of 6% hydroxyethyl starch (HES) 130/0.4 on postoperative blood loss and acute kidney injury (AKI) in patients undergoing off-pump coronary artery bypass grafting (OPCAB).Electronic medical records of 771 patients who underwent OPCAB in our hospital between July 2012 and July 2014 were reviewed, and 249 patients without intraoperative HES-exposure (group ...

BACKGROUND Significant bleeding with blood clot formation in the postoperative period may predispose to the formation of postoperative adhesions. A topical hemostatic agent would potentially improve postoperative comfort and lessen adhesion formation. This pilot study was performed to evaluate the effects of a novel topical hemostatic agent AMICAR (epsilon-aminocaproic acid; Xanodyne Pharmacal,...