Shuttling of specific proteins out of the nucleus is essential for the regulation of the cell cycle and proliferation of both normal and malignant tissues. Dysregulation of this fundamental process may affect many other important cellular processes such as tumor growth, inflammatory response, cell cycle, and apoptosis. It is known that XPO1 (Exportin-1/Chromosome Region Maintenance 1/CRM1) is t...

Introduction. The export potential of the regional agricultural market causes great interest from both scientific community and government agencies. Many studies are devoted to search for methods increase in order ensure sustainable development economic systems. article proposes tests original author’s algorithm creating a dynamic econometric model forecasting volumes production, sales exports ...

Nuclear mRNA export mediated by the human protein TAP requires a carboxy-terminal domain that directly interacts with components of the nuclear pore complex. Here we demonstrate that NXF3, a human RNA binding protein related to TAP, lacks this domain yet retains the ability to export tethered RNA transcripts and to shuttle between the nucleus and the cytoplasm. NXF3 contains a novel Crm1-depend...

The main purpose of this study was to determine the factors affecting the export of flowers in Iran. After data collection using by the index of Revealed Comparative Advantage (RCA), the condition of business of flowers in Iran was compared with a number of countries exporting the product. According to the results of study, the small elasticity of the exportation price in the function of export...

[1] Time-series datasets of surface-water biogenic silica (bSiO2) and deep-water bSiO2 export in the Santa Barbara Channel (SBC) allow for elucidation of the important scales of spatial and temporal variability and an evaluation of potential controlling mechanisms. Changes in local upwelling strength is the most important factor controlling seasonal variations for the surface bSiO2 dataset and ...

Export and the readiness to export constitute the first step of international marketing, which are affected by both internal and external factors of firms. One of the most important internal  factors is the presence of skilled personnel. The purpose of this study was to define the relationship between staff qualification and encouragment with the readiness level of Iranian pharmacuetical firms ...