sons who have been previously vaccinated. It will be seen on reference to Table I, giving account of Dr. Brailey's cases, and which will be found appended to this paper, that of sixteen persons who had each lost an eye as the result of smallpox, seven were admittedly unvaccinated, or 43 per cent.; and the average age at which these contracted small-pox was 8.9 years ; while the average age of f...

Background: Avipox virus considered to be a contagious disease of many types of birds wild and domestic. The current study focused on the isolation of recently common Avipox virus which include fowl pox (FP) and pigeon pox (PP) viruses in Iraq. Materials & methods: Isolation of the viruses was done via chorioallantoic membrane (CAM) route of avian embryo inoculation, also used by a chicken fibr...

Public health surveillance systems are important for tracking disease dynamics. In recent years, social and real-time digital data sources have provided new means of studying disease transmission. Such affordable and accessible data have the potential to offer new insights into disease epidemiology at national and international scales. We used the extensive information repository Google Trends ...

Type I hyperprolinemia (HPI) is an autosomal recessive disorder associated with cognitive and psychiatric troubles, caused by alterations of the Proline Dehydrogenase gene (PRODH) at 22q11. HPI results from PRODH deletion and/or missense mutations reducing proline oxidase (POX) activity. The goals of this study were first to measure in controls the frequency of PRODH variations described in HPI...

Lumpy skin disease (LSD, knopvelsiekte) is a pox disease of cattle characterised by fever, nodules 4 on the skin, mucous membranes and internal organs, emaciation, enlarged lymph nodes, oedema 5 of the skin, and sometimes death. The disease is of economic importance because it causes 6 reduced production, particularly in dairy herds. It also causes damage to the hide. LSD is caused by 7 strains...

Peroxiredoxin (Prx) was previously known as a Cys-dependent thioredoxin. However, we unexpectedly observed that Prx1 from the green spotted puffer fish Tetraodon nigroviridis (TnPrx1) was able to reduce H2O2 in a manner independent of Cys peroxidation and reductants. This study aimed to validate a novel function for Prx1, delineate the biochemical features and explore its antioxidant role in ce...

The authors reviewthe epidemiology of sheep pox outbreaks in Greece between 1987 and 2007. It is believed that sheep pox is introduced into Greece principally from neighbouring countries to the east, and is associated with the movements of infected sheep flocks close to the border and contacts between humans and animals. Disease foci have appeared in several central and north-eastern areas of t...

Aim The study was undertaken to assess the prevalence of antibodies to Capripoxviruses among small ruminants of Odisha, India. Materials and Methods A total of 500 random serum samples collected from 214 sheep and 286 goats across 10 agro-climatic zones of Odisha, were screened using whole virus antigen-based indirect ELISA for antibodies against Capripoxviruses. Results were analyzed by suit...

Peroxisome proliferator-activated receptor (PPAR)-gamma ligands have been shown to inhibit human lung cancers by inducing apoptosis and differentiation. In the present study, we elucidated the apoptotic mechanism of PPARgamma activation in human lung cancers by using a novel PPARgamma agonist, 1-(trans-methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-(1H-indene-2-carboxylic acid ethyl ester (...