Schistosomiasis (also known as bilharzia, bilharziasis, bilharziosis or snail fever) is a human disease syndrome caused by infection from one of several species of parasitic trematodes of the genus Schistosoma. Schistosomiasis is a major source of morbidity and mortality in many tropical and sub-tropical countries as well as for travelers from developed countries. Control of the disease depends...

Fourteen healthy adult Beagle dogs were included in this clinical study. Dogs randomly allocated to two study groups were treated on day 0 with a spot-on containing imidacloprid/moxidectin at the maximum approved dosage of 25 mg imidacloprid/kg bodyweight (bw) + 6.25 mg moxidectin/kg bw. Group 1 was treated at the same time orally with tablets containing emodepside/ praziquantel at the maximum ...

BACKGROUND  Schistosomiasis elicits cross-regulatory immune responses, but it is unclear how antihelminthic treatment affects this balance. This study integrates data on 13 cytokines elicited by 3 schistosome to examine how praziquantel treatment alters immune polarization and whether post-treatment cytokine profiles influence reinfection status. METHODS  Venous blood from 72 Schistosoma haem...

Introduction Giardiasis caused by Giardia lamblia is a worldwide health problem. Although mortality due to Giardiasis is generally low, massive infections can lead to considerable morbidity. This infection is more endemic in regions with poor sanitation, e. g. developing countries. Different rates such as 10.9% in the whole country [1] 26.2% in Damghan[2] and 7% in Ardabil [3] have been reporte...

A case of intraocular coenurosis was clinically diagnosed and treated with praziquantel. The drug destroyed the coenurus, but vision was lost through toxic endophthalmitis and retinal detachment. There were no systemic side effects.

An epidemiological study and control trial were conducted to assess taeniid infection in farm dogs in Qinghai Province, China. To improve egg detection by fecal examination, a deworming step with praziquantel was incorporated into the sampling methodology. As a result, a marked increase in the number of egg-positive samples was observed in samples collected at 24 hr after deworming. Then, the f...

A 26-year-old Brazilian man was admitted to The Toronto Hospital with a headache and visual scintillation. His last travel to Brazil was five years previously. A computed tomography (CT) scan of the head showed an occipital mass with surrounding vasogenic edema. Occipital brain biopsy revealed Schistosoma mansoni eggs. The patient was treated with two doses of praziquantel (20 mg/kg) and dexame...

Profound changes are occurring in the epidemiology of schistosomiasis, a neglected tropical disease caused by a chronic infection with parasitic helminths of the genus Schistosoma. Schistosomiasis currently affects 240 million people worldwide, mostly in sub-Saharan Africa. The advent and proliferation of mass drug administration (MDA) programmes using the drug praziquantel is resulting in subs...