This study uses information from the Central Pennsylvania Women’s Health Study (CePAWHS) to analyze health risk factors for adverse pregnancy outcomes in the Amish population of Lancaster County, Pennsylvania. A survey was conducted with 288 Amish woman and 2002 women from central PA. This study focuses specifically on how age (≤34 vs. ≥35), conception status (preconceptional, pregnant, interco...

Polycystic ovary syndrome (PCOS) is one of the most common complex and heterogeneous endocrine disorder in women with uncertain aetiology. The syndrome is associated with a wide range of symptoms and the diagnosis is based on the Rotterdam criteria. This review describes the currently available evidence regarding the therapeutic challenges raised in these women. Before any intervention is initi...

Marfan syndrome is an autosomal dominant disorder of connective tissue with up to 25% of cases related to a spontaneous mutation. It has been associated with perinatal loss, preterm labor and, potentially a rupture of the maternal aortic arch. We present a case of a woman diagnosed with Marfan syndrome after a miscarriage of her first pregnancy. At the time of diagnosis she had mild aortic bulb...