background & aim: preeclampsi which is a common and important disorder in pregnancy is one of the three leading causes of maternal mortality. it is worthy to find out an appropriate screening test for it. this study aimed to assess serum hematocrit level as a screening test for preeclampsia. methods & materials: using a randomized stratification, 660 women who were in the 24-28 weeks of gestati...

conclusions the levels of hemoglobin can be used to predict preeclampsia and monitoring the pregnant women and its regular measure in 3 trimesters help us to identify women at risk for preeclampsia. background preeclampsia is one of the most serious complications during pregnancy with important effects on health of mother and fetus that causes maternal and fetal morbidity and mortality. this st...

Preeclampsia is a clinical syndrome defined as the new onset of hypertension and proteinuria during the second half of pregnancy.1 It afflicts 3% to 5% of pregnancies and is a leading cause of maternal mortality, especially in developing countries.2,3 Because the only known remedy is delivery of the placenta, in developed countries preeclampsia is an important cause of premature delivery, usual...

BACKGROUND Preeclampsia is one of the most commonly encountered hypertensive disorders of pregnancy. For many years, obesity has been suggested to play a role in preeclampsia. However, the hypotheses have been diverse and often revealed inconsistent results. This study has aimed to estimate the effect of obesity and dietary habits on preeclampsia in Bahir Dar City, north-western Ethiopia. MET...

Response to Are Aldosterone Levels Inappropriately Low in Preeclampsia? Verdonk et al1 raise an interesting hypothesis that increased angiotensin II sensitivity and angiotensin II type 1 receptor autoantibodies in preeclampsia may not lead to inappropriately lower aldosterone levels, a hypothesis not supported by both experimental and clinical studies. In humans, aldosterone levels are relative...

BACKGROUND Hypertensive disorders of pregnancy are a major contributor to death and disability for pregnant women and their infants. The diagnosis of preeclampsia by using blood pressure and proteinuria is of limited use because they are tertiary, downstream features of the disease. Placental growth factor (PlGF) is an angiogenic factor, a secondary marker of associated placental dysfunction in...

BACKGROUND Although an increased risk of preeclampsia in pregnancies conceived by in vitro fertilization (IVF) has been reported, it remains unknown whether IVF is associated with preeclampsia. In the present study, we sought to investigate whether IVF is associated with preeclampsia in pregnant women using propensity score matching analysis. METHODS This study included 3,084 pregnant women w...

preeclampsia is a major cause of morbidity and mortality during pregnancy. several independent investigators have demonstrated the association of androgens with hypertension. the main purpose of this study was to determine whether maternal levels of sex hormones, especially testosterone, are higher in patients with preeclampsia than in matched normotensive control subjects. serum levels of test...

Background: Household food insecurity is defined as the limited or uncertain access to adequate and safe food or limited ability to obtain food in a socially acceptable manner. Preeclampsia is a severe case of high-risk pregnancy, which endangers the health of women across the world, especially in developing countries. The current study aimed to use the nutritional deficiencies theory in pathog...

OBJECTIVES Preeclampsia is a multisystem disease that significantly contributes to maternal and foetal morbidity and mortality. In this study, we used a nonbiased microarray approach to identify novel circulating miRNAs in maternal plasma that may be associated with preeclampsia. METHODS Plasma samples were obtained at 16 and 28 weeks of gestation from 18 women who later developed preeclampsi...