BACKGROUND Enlargement of the lateral ventricles is thought to originate from abnormal prenatal brain development and is associated with neurodevelopmental disorders. Fetal isolated mild ventriculomegaly (MVM) is associated with the enlargement of lateral ventricle volumes in the neonatal period and developmental delays in early childhood. However, little is known about postnatal brain developm...

Both otoacoustic emissions (OAEs) and auditory evoked potentials (AEPs) are sexually dimorphic, and both are believed to be influenced by prenatal androgen exposure. OAEs and AEPs were collected from people affected by 1 of 3 categories of disorders of sex development (DSD) - (1) women with complete androgen insensitivity syndrome (CAIS); (2) women with congenital adrenal hyperplasia (CAH); and...

The prenatal phase of life is a critical period for brain development. It is a crucial period for the formation of structural and functional integrity of the brain with the combination of various factors in the unique environment of the uterus. It is a period of manifold interactions that are essential biological conditions for the continuous development of the human brain and it is also a part...

There is increasing interest in and evidence for altered immune factors in the etiology and pathophysiology of schizophrenia. Stimulated by various epidemiological findings reporting elevated risk of schizophrenia following prenatal exposure to infection, one line of current research aims to explore the potential contribution of immune-mediated disruption of early brain development in the preci...

A significant proportion of fetal anomalies are surgically correctable. Their accurate and reliable prenatal diagnosis is of great importance, and will have significant influence on both postnatal and postsurgical outcome. The influence of prenatal diagnosis of simple structural defects will interfere with organ development. In the light of recent achievements, traditional teratology has to be ...

Understanding the development of a skull deformity requires an understanding of the normal morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of one or more cranial sutures leading to skull deformities. A review of the English medical literature using textbooks and standard search engines was performed to gather information about the prenatal development an...

Many prenatal risk factors are known to have adverse consequences on fetal development and there is increasing interest in effects on the mental health of offspring. However, associations with prenatal risk factors may arise because of postnatal risk or through confounders, including inherited ones. As a result, caution is required in assuming causation.

This study presents the development of the corneal epithelium of the mouse in chronological sequence covering the early prenatal, late prenatal, and postnatal periods, until the time of the disappearance of lid adhesion. The work is based on electron microscopic study of the corneal epithelium at daily intervals from the eleventh day of gestation to the seventh postnatal day, as well as the ten...

BACKGROUND Prenatal alcohol exposure may be a risk factor for the development of alcohol problems in humans. METHODS We use data beginning with interviews of women in prenatal care at midpregnancy to predict alcohol use and alcohol-related problems in their offspring now aged 21 years. Maternal drinking during pregnancy was assessed from November 4, 1974, through October 2, 1975, along with m...

the outcome and proper management of fetal hydronephrosis have not been completely defined. the purpose of this study was to determine incidence and outcome of infants with a history of prenatal hydronephrosis diagnosed by ultrasound. in a three-year period from 2000 to 2003 we identified 211 cases (271 renal units) of fetal hydronephrosis in which renal pelvic anteroposterior diameter was more...