Introduction: The term glaucoma refers to a group of diseases that have a characteristic optic neuropathy with associated visual field loss in common. Intraocular pressure has been considered to be the only causal factor for glaucoma and the only factor that can be manipulated to alter the course of the disease. But considering high intraocular pressure as the only factor responsible for glauco...

A general framework is presented for accurately and efficiently estimating the phenomenological pressure-dependent rate coefficients for reaction networks of arbitrary size and complexity using only high-pressure-limit information. Two aspects of this framework are discussed in detail. First, two methods of estimating the density of states of the species in the network are presented, including ...

Introduction The so called hyper-CEST method promises tremendous potential on molecule-specific MR imaging using hyperpolarized Xe caged in functionalized cryptophane cages [1]. It was shown that these biosensors can be utilized as highly sensitive temperature probes [2] and that molecule-specific signals in the lower nM regime can be detected when experimental parameters are optimized to yield...

High-pressure torsion (HPT) is a metal processing method in which the sample is subjected to a very high plastic shear deformation. This process can produce exceptional levels of grain refinement, and provides a corresponding improvement in mechanical properties. To investigate the stress and strain distribution due to HPT process finite element simulation were conducted to investigate effectiv...

The narrow operating window between pore pressure and fracture pressure makes drilling difficult in some operations. A feasibility study of managed pressure drilling (MPD) is carried out on Iran Darquain oil field. The previous wells drilled in this field showed that mud returns were lost during drilling Gadvan formation. The present work addresses this problem by means of surface back pressure...