The association of preterm birth with obesity and metabolic syndrome later in life is well established. Although the biological mechanism for this association is poorly understood, epigenetic alterations of metabolic-related genes in early life may have important roles in metabolic dysfunction. Thus, we investigated the associations of DNA methylations of melanocortin 4 receptor (MC4R) and hepa...

OBJECTIVE There are indications that the prevalence of exclusively breastfed preterm infants is decreasing in Sweden. The objective was to investigate trends in exclusive breast feeding at discharge from Swedish neonatal units and associated factors in preterm infants. DESIGN, SETTING AND PARTICIPANTS This is a register study with data from the Swedish Neonatal Quality Register. Data from 29 ...

 Background Feeding intolerance is one of the leading causes of weight loss in preterm infants. The present study aimed to evaluate the effects of abdominal massage on feeding tolerance in preterm infants hospitalized in neonatal intensive care units in Isfahan, Iran. Materials and Methods: In this randomized controlled clinical trial, 64 infants who had the inclusion criteria, were selected an...

IMPORTANCE Recommendations concerning the appropriate age threshold for respiratory syncytial virus (RSV) prophylaxis in moderate-preterm infants are highly debated. OBJECTIVE To determine the age at which moderate-preterm infants' risk of RSV hospitalization has decreased to the risk observed in low-risk term infants. DESIGN, SETTING, AND PARTICIPANTS Retrospective cohort study of Florida and ...

recombinant human erythropoietin (rh-epo) is known to accelerate erythropoiesis in preterm infants. the purpose of this study was to compare the effectiveness of early treatment with two doses of rh-epo (high vs. low dose) in the management of anemia of prematurity. twenty preterm infants with hematocrit (hct) < 30% when infant’s age was between 2 to 3 weeks after birth or hct <25% when infant’...

AIM The study was conducted to evaluate the immunogenicity of an early, extra dose of enhanced inactivated poliovirus vaccine (IPV) administered simultaneously with recombinant hepatitis B vaccine (HBV) to preterm infants shortly after birth. METHODS Three groups were studied. Fifty preterm infants received IPV intramuscularly within 24 hours of birth, in addition to routine recommended child...

BACKGROUND Evidence for protection of preterm born infants from invasive pneumococcal disease (IPD) by 7-valent pneumococcal conjugate vaccination (PCV7) is relatively sparse. Data from randomized trials is based on relatively small numbers of preterm born children. METHODS We report data from active prospective surveillance of IPD in children in Germany. The cohorts of preterm born children ...

Background: Feeding intolerance is a major concern in preterm infants. Appropriate position during feeding is one of the interventions that nurses can exploite in order to improve the feeding tolerance in preterm infants. Aim: Comparison of the effect of nutrition in the kangaroo mother care and supine position on gavage residual volume in preterm infants. Methods: Thisrandomized single-blind c...

To detect differences between late preterm and term infants in the brainstem auditory evoked response (BAER) variables that predispose to neurodevelopmental abnormalities, 36 late preterm infants and 87 term infants were recruited. Data collected with the click level at 70 dB nHL were used for analysis. The latencies of waves I (2.74±0.20 msec vs. 2.74±0.42 msec), III (5.55±0.33 msec vs. 5.53±0...

Preterm infants are at increased risk for cognitive disorders, including impairments in recognition memory. This study evaluated the effects of extreme prematurity on the neural pathway for auditory recognition memory using event-related potentials (ERPs), a neurophysiological technique widely used in cognitive neuroscience. ERPs were recorded at term postmenstrual age in 35 preterm infants bor...