We des ribe a xed point approa h for the following sto hasti optimization problem: given a multi ast tree and probability distributions of user utilities, ompute pri es to o er the users in order to maximize the expe ted pro t of the servi e provider. We show that any optimum pri ing is a xed point of an eÆ iently omputable map. In the language of lassi al numeri al analysis, we show that the n...

This paper presents an automatic de-identification system for Serbian, grounded on a rapid adaptation of the existing named entity recognition system. Based on a finite-state methodology and lexical resources, the system is designed to detect and replace all explicit personal protected health information present in the medical narrative texts, while still preserving all the relevant medical con...

T he genomes of higher eukaryotes encode not only proteins but also diverse noncoding RNAs, particularly small (20to 30-nt) regulatory RNAs (1–3). The small RNAs include microRNAs (miRNAs), siRNAs, and piwi-interacting RNAs (piRNAs) (4, 5). These small RNAs repress gene expression at the transcriptional or posttranscriptional levels and have critical functions in genome defense, growth, develop...

A module M is called epi-retractable if every submodule of M is a homomorphic image of M. Dually, a module M is called co-epi-retractable if it contains a copy of each of its factor modules. In special case, a ring R is called co-pli (resp. co-pri) if RR (resp. RR) is co-epi-retractable. It is proved that if R is a left principal right duo ring, then every left ideal of R is an epi-retractable ...

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BACKGROUND/AIM Colchicine (COL) is a well-known and potent microtubule targeting anticancer agent. The purpose of our study was to identify conditions that increase sensitization of COL-resistant cancer cells that overexpress P-glycoprotein (P-gp). MATERIALS AND METHODS The anti-malarial drugs chloroquine (CHL), mefloquine (MEF) and primaquine (PRI) have been shown to increase sensitization i...

A series of diurnal airborne campaigns were conducted over an orchard field to assess the canopy Photochemical Reflectance Index (PRI) as an indicator of water stress. Airborne campaigns over two years were conducted with the Airborne Hyperspectral Scanner (AHS) over an orchard field to investigate changes in PRI, in the Transformed Chlorophyll Absorption in Reflectance Index (TCARI) normalized...

While functional mature microRNAs (miRNAs) are small ∼22 base oligonucleotides that target specific mRNAs, miRNAs are initially expressed as long transcripts (pri-miRNAs) that undergo sequential processing to yield the mature miRNAs. We have previously reported that the pri-miR-17∼92 cluster adopts a compact globular folded structure that internalizes a 3' core domain resulting in reduced miRNA...

Periodic pulse trains can represent the emissions of a pulsed source or the \look" pattern of a scanning receiver. The distribution in time of pulse overlaps is considered for two strictly periodic pulse trains. The probability of at least one pulse overlap within a given time is found for a periodic pulse train with a staggered or jittered pulse train. These questions are important in understa...

MicroRNA (miRNA) biogenesis proceeds from a primary transcript (pri-miRNA) through the pre-miRNA into the mature miRNA. Here, we identify a role of the Caenorhabditis elegans nuclear export receptor XPO-1 and the cap-binding proteins CBP-20/NCBP-2 and CBP-80/NCBP-1 in this process. The RNA-mediated interference of any of these genes causes retarded heterochronic phenotypes similar to those obse...