Lymphoproliferative disease (LPD) is a recognized complication of primary immunodeficiency (PID) and immunodysregulatory syndromes. Historically, it has a very poor outcome. For patients surviving LPD, myeloablative hematopoietic stem cell transplantation (SCT) was the only cure for the underlying PID, with a high risk of developing posttransplantation complications, including recurrent lymphop...

background: intestinal protozoa transmitted by food are the most common opportunistic parasites among the hiv+/aids patients. as, there is no report about prevalence of food-borne intestinal parasites in such patients in yazd, so this study was performed to determine the prevalence of intestinal protozoa in the hiv+/aids patients in comparison with hiv- individuals. methods: a case-control stud...

The primary immunodeficiency diseases are a heterogeneous group of over 50 disorders which affect the cells, tissues and proteins of the immune system. These disorders were originally felt to be rare, to occur only in infants and young children and to be associated with severe clinical symptoms. However, as clinical experience with the primary immunodeficiency diseases has grown, it has become ...

Background: Frequent infections is among the most frequent clinical dilemmas for primary care physicians. Immunodeficiency disorders are a heterogeneous group of illnesses that predispose patients to the recurrent infections, autoimmunity and malignancies. The aim of this study was to evaluate the clinical and laboratory data collected for the final diagnosis of patients referred with recurrent...

Pelvic inflammatory disease (PID) is a substantial cause of reproductive morbidity in young women. A systematic review of the literature related to PID management was performed in preparation for the 2006 Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelines. This search was conducted using PubMed and was limited to articles written in English and publish...

We retrospectively analyzed the outcomes of hematopoietic stem cell transplantation in 7 patients with primary immunodeficiency diseases treated at the National University Hospital, Singapore, over the period from December 1996 to January 2010. The primary immunodeficiency diseases managed were X-linked hyperimmunoglobulin M syndrome (n = 3), severe combined immunodeficiency (n = 1), leukocyte ...