Această lucrare descrie tehnici specializate de extragere a modelelor nominale şi parametrice pentru interconexiunile lungi descompuse în linii drepte, modelate ca linii de transmisie şi în componente de joncţiune, modelate ca dispozitive pasive. Un pas important în modelare este extragerea parametrilor lineici pentru linia de transmisie. Este prezentată o nouă abordare pentru calculul conducta...

C. A. Azlan, P. Di Giovanni, T. S. Ahearn, W. M. Prins, M. Clemence, S. I. Semple, F. J. Gilbert, and T. W. Redpath Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, United Kingdom, Department of Biomedical Imaging, University of Malaya, Kuala Lumpur, Malaysia, Philips Healthcare, Best, Netherlands, Philips Healthcare, Reigate, England, United Kingdom, Department o...

DNA vaccination is a promising strategy to induce effector T cells but also regulatory Foxp3(+) CD25(+) CD4(+) Treg cells and inhibit autoimmune disorders such as type 1 diabetes. Little is known about the antigen requirements that facilitate priming of Treg cells but not autoreactive effector CD8(+) T cells. We have shown that the injection of preproinsulin (ppins)-expressing pCI/ppins vector ...

The 2-oxa-5-adamantyl carbocation 4 is shown to be a viable intermediate in several S(N)1 substitution reactions. However, attempts to observe the formation of 4 from various precursors by NMR methods (which succeed for the 1-adamantyl cation 5) failed, suggesting that 4 does not survive on longer timescales. DFT calculations suggest that the retro-Prins process (beta-cleavage, Grob fragmentati...

The present paper is aimed at solving initial value problems by the contraction-mapping principle in case an interior estimate is true in the function space under consideration. reziume. naSr omis mizania saCKisi amocanis kumSviTi asaxvis prin-cipiT amoxsna im SemT xvevaSi, roca gansaxil vel sivr ceSi samar Tl iania pirvel i rigis Carmoebu l ebis SePaseba gansazG vr is aris SigniT mo-Tavsebu l ...

A sustainable and simple Au(I) catalytic system to synthesise 8-oxabicyclo[3.2.1]oct-2-enes and 9-oxabicyclo[3.3.1]nona-2,6-dienes from enynol via oxonium/Prins-type cyclization is described. The key advantages of this reaction are selectivity, good functional group tolerance and a new approach for synthesis of oxabicyclic and oxatricyclic systems.

The formal synthesis of (+)-SCH 351448 has been accomplished with the catalytic Prins cyclization strategy, yielding the monomeric unit as a single isomer.

An acetal-initiated Prins bicyclization approach has been developed for the stereoselective synthesis of hexahydrofuro[3,4-c]furan lignans. This also provides a direct way to generate a new series of octahydropyrano[3,4-c]pyran derivatives in a single-step process.