نتایج جستجو برای: primidone

تعداد نتایج: 231  

Journal: Pollution 2018
M Usman M Waseem N Andiego N Mani

Trace organic compounds (TrOCs), mostly found in secondary effluents, have a potential impact on the environment, affecting surface water, groundwater, and especially aquatic ecosystems. The present study focuses on oxidation of five selected TrOCs in column experiments, by simulating Soil Aquifer Treatment (SAT) integrated with Fenton-like reaction, using Granular Ferric Hydroxide (GFH) as a c...

2014
Marlies Bergheim Richard Gminski Bernd Spangenberg Malgorzata Dębiak Alexander Bürkle

Data allowing for a complete environmental risk assessment of pharmaceuticals and their photoderatives in the environment are still scarce. In the present study, in vitro toxicity and both bioand photopersistence of various pharmaceuticals (aciclovir, allopurinol, cetirizine, cimetidine, fluconazole, hydrochlorothiazide, lisinopril, phenytoin, primidone, ranitidine, sotalol, sulpiride, tramadol...

Journal: :British journal of clinical pharmacology 2006
Emilio Perucca

Some patients with difficult-to-treat epilepsy benefit from combination therapy with two or more antiepileptic drugs (AEDs). Additionally, virtually all epilepsy patients will receive, at some time in their lives, other medications for the management of associated conditions. In these situations, clinically important drug interactions may occur. Carbamazepine, phenytoin, phenobarbital and primi...

Journal: :Neurology 2009
C L Harden P B Pennell B S Koppel C A Hovinga B Gidal K J Meador J Hopp T Y Ting W A Hauser D Thurman P W Kaplan J N Robinson J A French S Wiebe A N Wilner B Vazquez L Holmes A Krumholz R Finnell P O Shafer C Le Guen

OBJECTIVE To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid use, prenatal vitamin K use, risk of hemorrhagic disease of the newborn, clinical implications of placental and breast milk transfer of antiepileptic drugs (AEDs), risks of breastfeeding, and change in AED levels during pregnancy. MET...

Journal: :American journal of epidemiology 2001
S Hernández-Díaz M M Werler A M Walker A A Mitchell

Periconceptional folic acid supplementation reduces the risk of neural tube defects (NTDs). To determine whether periconceptional exposure to folic acid antagonists (FAAs) might therefore increase the risk of NTDs, the authors examined data from an ongoing case-control study of birth defects (1979-1998) in the United States and Canada. They compared data on 1,242 infants with NTDs (spina bifida...

2013
Riccardo Davanzo Sara Dal Bo Jenny Bua Marco Copertino Elisa Zanelli Lorenza Matarazzo

INTRODUCTION This review provides a synopsis for clinicians on the use of antiepileptic drugs (AEDs) in the breastfeeding mother. METHODS For each AED, we collected all retrievable data from Hale's "Medications and Mother Milk" (2012), from the LactMed database (2013) of the National Library of Medicine, and from a MedLine Search of relevant studies in the past 10 years. RESULTS Older AEDs,...

Journal: :Environment international 2013
Xiaoqin Wu Frederick Ernst Jeremy L Conkle Jay Gan

Reuse of treated wastewater to irrigate agricultural crops is increasing in many arid and semi-arid areas around the world. The presence of numerous pharmaceutical and personal care products (PPCPs) in treated wastewater and their potential transfer into food produce such as vegetables poses an unknown human health risk. The goal of this study was to identify PPCPs that have a comparatively hig...

2016
Chun-Hai Wei Christiane Hoppe-Jones Gary Amy TorOve Leiknes

The removal of 15 organic micro-pollutants (OMPs) in synthetic municipal wastewater was investigated in a laboratory-scale mesophilic anaerobic membrane bioreactor (AnMBR) using ultrafiltration and AnMBR followed by nanofiltration (NF), where powdered activated carbon (PAC) was added to enhance OMPs removal. No significant effects of OMPs spiking and NF connection on bulk organics removal and b...

Journal: :Water Research 2021

The UV/chlorine process as a potential tertiary municipal wastewater treatment alternative for removing refractory PPCPs has been widely investigated. However, the role of effluent organic matter (EfOM) on radical chemistry and toxicity alteration is unclear. elimination two model PPCPs, primidone (PRM) caffeine (CAF), by co-exposure UV free chlorine was investigated to elucidate impact EfOM. E...

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