Since ancient times, India has used its rich knowledge of traditional medicine to prevent and cure diseases. Herbal medicines have fewer side effects in comparison with traditional medicines, but side effects do occur. There are many species of medicinal plants belonging to various families which are being used, traditionally, to control and cure a variety of dental problems by the Indian popul...

Formulating etoposide into a nanoemulsion based on combining two natural oils, Ribes nigrum (black currant) seed oil and organic evening primrose oils may improve its antineoplastic activity in cancer cells. The present study aimed to synthesize, characterize vitro evaluate the cytotoxic effect of formulating etoposide-loaded Colorectal Carcinoma colon anti-proliferation anti-invasion effects p...

OBJECTIVE Little data is available on complementary and alternative medicine (CAM) use in children attending otolaryngology services. We investigated the prevalence and pattern of CAM use among children attending the pediatric otolaryngology department in a tertiary pediatric teaching hospital in Scotland. DESIGN A cross-sectional survey conducted by administering an anonymous questionnaire t...

Randomized controlled trials of the effects of the dietary supplement Efacal (Scotia Pharmaceuticals Plc, Guildford, Surrey, UK) v. Ca only on total body bone mineral density (BMD) and markers of bone turnover were conducted in healthy pre- and postmenopausal women separately. Total daily dose for 12 months for the Efacal groups was: Ca 1.0 g, evening primrose oil 4.0 g and marine fish oil 440 ...

The dominant orthodox biological concept of schizophrenia is that it is somehow related to an excess of dopamine activity in critical areas of the brain. The outstanding pieces of evidence in favor of this concept are that all the commonly used anti-schizophrenic drugs are blockers of dopamine receptors and that two groups have now reported that certain regions of the brain in schizophrenics ex...

BACKGROUND Hot flashes are the most common symptoms experienced by women around the time of menopause. Many women are interested in herbal medicines because of fear of side effects of hormone therapy. OBJECTIVE The aim of this systematic review was to assess the effectiveness of Iranian herbal medicines in alleviating hot flashes. MATERIALS AND METHODS MEDLINE (1966 to January 2015), Scopus...

INTRODUCTION Atopic dermatitis (AD) has been related to a deficiency of delta-6-desaturase, an enzyme responsible for the conversion of linoleic acid to gamma-linolenic acid (GLA). Evening primrose oil (EPO) contains high amounts of GLA. Therefore, this study investigated whether EPO supplementation results in an increase in plasma GLA and its metabolite dihomo-gamma-linolenic acid (DGLA) corre...

Nerve crush injuries are commonly used models for axonotmesis to examine peripheral nerve regeneration. As evening primrose oil (EPO) is rich in omega-6 essential fatty acid component and gamma-linolenic acid, studies have shown the potential role of EPO in myelination. Seventy-two healthy adult Sprague-Dawley rats were classified into three groups: normal group, control group, and experimental...