background: the natural history and etiology of malignant mesothelioma (mm) is already thoroughly described in the literature, but there is still debate on prognostic factors, and details of asbestos exposure and possible context with clinical and demographic data, have not been investigated comprehensively. objectives: description of patients with mm, focusing on exposure, occupation, survival...

Impaired glucose tolerance influences the prognosis of hepatocellular carcinoma (HCC), but this mechanism is still not fully understood. We investigated the impact of the fasting serum levels of insulin and adiponectin on the prognosis of HCC and its recurrence. One hundred and forty patients with newly diagnosed HCC were enrolled in the prognosis study. Their fasting serum levels of insulin an...

.........................................................................................................................5 I REVIEW OF THE LITERATURE...................................................................................8 1 ASBESTOS FIBRES .........................................................................................................8 1.1.1 Oxidative stress and antioxidant...

discussion children with congenital heart disease are at risk of acquiring gram-negative endocarditis even if they have not had other predisposing factors. case presentation in this study a ten-year-old boy with ventricular septal defect, who was not immune compromised and acquired klebsiella endocarditis is introduced. the patient had a favorable response to medical treatment and underwent a s...

Oral drugs stimulating endogenous insulin production (insulin secretagogues) may have detrimental effects on breast cancer outcomes. The data presented shows the relationship between pre-existing insulin secretagogues use, adipokine profiles at the time of breast cancer (BC) diagnosis and subsequent cancer outcomes in women diagnosed with BC and type 2 diabetes mellitus (T2DM). The Pearson corr...

Gender-specific medicine studies how sexual biology and gender-related cultural behavioral differences may influence a person’s health considers the in clinical features, prevention, therapies, prognosis, psycho-social aspects of diseases with different impacts on women men. The present work summarizes main differential impact each risk factor for oral cancer periodontitis has according to biol...

Non-small cell lung cancer (NSCLC) accounts for approximately 80-85% of all lung cancer cases. Cigarette smoking is the number one risk factor which is attributed to more than four out of five cases of lung cancers. The prognostic impact of cell cycle regulation-associated tumor suppressors including p53 and p21 for NSCLC is still controversial. In the present study, we examined p53 and p21 exp...

BACKGROUND This study was designed to evaluate the plasma levels of tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in patients with unstable angina and investigate whether there is a relationship between these levels and unfavorable outcome. METHODS AND RESULTS The plasma TF and free TFPI antigen levels were determined in plasma samples taken from 51 patients with unstable angi...

the aim of this study was investigating the characteristic and outcome of self-immolation cases admitted to the burn centre of birjand, iran over an eight year period. this study is a retrospective review of case notes for patients with self-immolation and admitted to our referral burn centre in the last 8 years (january 2003-january 2011). a performa was designed to collect the data such as: d...