The aim of this research was to determine whether all memory T cells have the same propensity to migrate to the joint in patients with juvenile idiopathic arthritis. Paired synovial fluid and peripheral blood mononuclear cell proliferative responses to a panel of antigens were measured and the results correlated with a detailed set of laboratory and clinical data from 39 patients with juvenile ...

Background Cysteine-rich protein 61 (CYR61/CCN1) is a growth factor-inducible gene, involved in the regulation of multiple cellular processes, such as cell adhesion, migration, survival, growth factor-induced mitogenesis, endothelial tubule formation, apoptosis and angiogenesis. In normal women endometrium, CYR61 expression is elevated during the proliferative phase of the menstrual cycle, and ...

1. What events occur during each of the primary phases of wound healing? Wound healing has three principal phases: inflammatory, proliferative, and remodeling. The inflammatory phase begins at the time of injury and lasts for 24 to 48 hours. This phase begins with hemostasis and leads to inflammation. Platelets form the initial thrombus release growth factors that induce the chemotaxis and prol...

In the present study, we analyzed the cell cycle distribution of bone marrow (BM) cells in 120 untreated multiple myeloma patients using a DNA/CD38 double-staining technique at flow cytometry in which plasma cells (PCs) can be clearly discriminated from residual BM cells based on their CD38 expression. This approach allows us to determine the proliferative activity of both PCs and residual norm...

Background: Histopathology of endometrium is considered important investigation in case infertility. The functional disturbance involved infertility may result morphological changes endometrium. Endometrial histopathology helpful dating so that hormonal status, ovulation and infertility.Methods: material for this study consists endometrial tissue obtained from patients. It was collected either ...

The structural change in the tight junction between human endometrial epithelial cells during the normal menstrual cycle was observed by means of freeze-fracture replica electron microscopy. Tight junctions between epithelial cells of the endometrial basal layer showed no alterations in structure during the menstrual cycle, while those between epithelial cells of the functional layer exhibited ...

S-phase fraction, an index of cellular proliferation, and DNA ploidy were measured by DNA flow cytometry in a retrospective study of lymph node biopsy specimens from 83 cases (before treatment) of follicular non-Hodgkin's lymphoma, Working Formulation categories B and C. The correlations between these measures and survival, clinical stage, symptoms and histopathological factors were investigate...

The pathogenesis of leiomyoma may be related to an imbalance in the interaction of sex steroids with paracrine growth factors that may control the modulation of mitogenesis and local immunity. The authors investigate the temporal and spatial expression of proliferative and preapoptotic molecules that may participate in the modulation of myometrial function and leiomyoma pathogenesis. Immunohist...