PURPOSE To evaluate retrospectively clinical features and surgical outcomes of rhegmatogenous retinal detachment in juvenile patients. METHODS Between 1991 and 1996, 28 patients younger than 15 years of age with rhegmatogenous retinal detachment (32 eyes) underwent the first surgical procedure, scleral buckling and/or pars plana vitrectomy, at our hospital. RESULTS The major types of juveni...

The introduction of pars plana vitrectomy in clinical ophthalmology by Robert Machemer and colleagues was a profound paradigm change which opened up new avenues for the treatment of ocular diseases, such as proliferative vitreoretinopathy, which up to that time had been incurable [79]. It was again Robert Machemer who together with Yasuo Tano, Gholam Peyman, Stephan Ryan and other researchers f...

OBJECTIVE To review fibrosis of fluocinolone acetonide (FA) implants in subjects with CAPN5 autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV). METHODS A retrospective case series was assembled from ADNIV patients in which there was fibrotic encapsulation of a fluocinolone acetonide implant. CAPN5 genotypes and surgical repair techniques were reviewed. RESULTS Two eyes of...

Twenty-eight patients with rhegmatogenous retinal detachment were treated by pneumatic retinopexy using intravitreal perfluorpropane (C3F8) gas. Reattachment was successfully achieved in 22 eyes (78.6%) after one treatment. Most of the eyes were myopic and had a single retinal break or group of breaks within one o'clock hour. All retinal complications developed in the inferior retinal quadrants...

BACKGROUND: Eye injury is an actual problem, occupying a leading position among the main causes of blindness and low vision, accounting for 22.8% in structure primary visual disability, which 53% cases are due to closed eye injury. Despite development widespread introduction into practice methods high-tech care patients this profile, there number complications that poorly respond treatment, ult...

PURPOSE. In many cell types, tumor necrosis factor (TNF)– induced apoptosis is prevented by production of TNF– induced antiapoptotic protein, a process mediated by nuclear transcription factor (NF)B. TNFis widely expressed in proliferative vitreoretinopathy (PVR) membranes and is present in the vitreous of eyes with PVR. To understand mechanisms responsible for RPE cell survival and death in th...