نتایج جستجو برای: prolonged qtc interval

تعداد نتایج: 283643  

Journal: :Heart 1998
J Kazmierczak Z Kornacewicz-Jach M Kisly R Gil A Wojtarowicz

OBJECTIVE To report acute and mid-term electrocardiographic changes in patients with hypertrophic obstructive cardiomyopathy (HOCM) after alcohol ablation of the first large septal branch of the left anterior descending coronary artery; and to relate electrocardiographic data with the left ventricular outflow tract pressure gradients. PATIENTS Nine consecutive symptomatic patients with HOCM (...

Journal: :BMJ case reports 2014
Benjamin B Albert Luke Gerard Eckersley Jonathan Robert Skinner Craig Jefferies

A 12-year-old girl presented with an acute confusional state and a 2-year history of weight loss, anxiety, agitation and recurrent fever. Thyroid function tests confirmed severe hyperthyroidism, and a diagnosis of thyroid storm was made (Burch and Wartofsky score=75). ECG showed a prolonged QTc interval of 506 ms. Acute treatment for thyroid storm consisted of Lugol's iodine, prednisolone, carb...

Journal: :Journal of clinical pharmacology 2012
Asif Naseem Tomohiko Harada Duolao Wang Radivoj Arezina Ulrike Lorch Erol Onel Alan John Camm Jorg Taubel

1441 2012 52 1441-1447 Following surgery, effective postsurgical pain management is essential because most patients experience pain that often persists for several days or even weeks. For a wide range of surgical procedures, local anesthetics administered via an epidural injection, peripheral nerve blocks, or local infiltrations are commonly used to provide postoperative analgesia. However, the...

2012
A. Tounsi L. Abid M. Akrout M. Hentati S. Kammoun

We present the case of a 49-year-old male patient with prosthetic mitral valve endocarditis associated with QT prolongation and torsades de pointes. He was asymptomatic until the end of January 2012, when he was admitted to our hospital emergency unit because of syncope, fever, and suspicion of endocarditis. Cardiologic evaluation was requested and the transthoracic (TTE) and transesophageal (T...

ابریشم کار, سعید , ایری, عبدالرزاق , عباسی فر, سلمان , مومنی, علی ,

چکیده: زمینه و هدف: از علل مهم مرگ و میر بخصوص در جوامع شهری و صنعتی آسیب های تروماتیک مغزی است. از جمله اختلالات الکتروکاردیوگرافی (ECG) در آسیب های تروماتیک مغز تاکی آریتمی ها، برادی آریتمی ها، افزایش فاصله (interval) QTc و تغییرات قطعه ST می باشد. در بیماران با ترومای مغزی از جمله خونریزی ساب ارکنویید (SAH) طولانی شدن QTc interval گزارش شده است. این مطالعه با هدف بررسی فراوانی و شدت افزایش ...

Background: We designed a cross-sectional study to determine electrocardiographic disorders in Down syndrome patients with congenitally normal hearts in a bid to predict fatal cardiac arrhythmia in the future. Materials and Methods: We investigated 60 children with DS without congenital abnormal hearts. Sixty healthy juveniles were also included in the study as a control group. Physical examina...

2014
Feng Zhao Suyang Cui Libing Huang

Aim. This study investigated the effect of P6 EA on droperidol-induced QTc interval prolongation and Cx43 expression in ventricular muscle of rats. Methods. Twenty-four rats were randomly divided into control group (C), droperidol group (D), or EA group (E). C group rats were injected with normal saline. D group rats were injected with droperidol 0.13 mg/kg. E group rats were pretreated with EA...

2014
Lea T. Drye David Spragg D. P. Devanand Constantine Frangakis Christopher Marano Curtis L. Meinert Jacobo E. Mintzer Cynthia A. Munro Gregory Pelton Bruce G. Pollock Anton P. Porsteinsson Peter V. Rabins Paul B. Rosenberg Lon S. Schneider David M. Shade Daniel Weintraub Jerome Yesavage Constantine G. Lyketsos

BACKGROUND A Food and Drug Administration (FDA) safety communication in August 2011 warned that citalopram was associated with a dose dependent risk of QT prolongation and recommended dose restriction in patients over the age of 60 but did not provide data for this age group. METHODS CitAD was a randomized, double-masked, placebo-controlled, multicenter clinical trial for agitation in Alzheim...

Journal: :Pediatric pulmonology 2008
Jerome O Gronli Barbara A Santucci Sue E Leurgans Elizabeth M Berry-Kravis Debra E Weese-Mayer

OBJECTIVE Children with Congenital Central Hypoventilation Syndrome (CCHS) have cardiovascular symptoms consistent with the autonomic nervous system dysregulation/dysfunction (ANSD) phenotype. We hypothesized that children with CCHS would have a relationship between PHOX2B genotype and two clinically applicable cardiovascular measures of ANSD: duration of longest r-r interval and longest correc...

Journal: :Molecular medicine reports 2014
Baoxin Liu Shuang Li Yang Su Mengting Xiong Yawei Xu

Terfenadine is a second generation histamine receptor antagonist which is widely used as a non‑sedating antihistamine to relieve allergic responses. However, terfenadine has been associated with a number of side effects on cardiac electrical activities through blocking multiple ion channels in the heart, particularly K+ channels. Previous studies have also implied that terfenadine may have a po...

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