OBJECTIVE To investigate the feasibility of testing for prostate cancer and the prevalence and characteristics of the disease in unselected young men. DESIGN Prospective cohort nested within a randomised controlled trial, with two years of follow-up. SETTING Eight general practices in a UK city. PARTICIPANTS 1299 unselected men aged 45-49. INTERVENTION Prostate biopsies for participants...

PURPOSE To our knowledge the role of magnetic resonance imaging as a first line screening test for prostate cancer is unknown. We performed a pilot study to evaluate the feasibility of prostate magnetic resonance imaging as the primary screening test for prostate cancer. MATERIALS AND METHODS We recruited unselected men from the general population. Prostate multiparametric magnetic resonance ...

PURPOSE Despite earlier detection and stage migration, seminal vesicle invasion is still reported in the prostate specific antigen era and remains a poor prognostic indicator. We investigated outcomes in men with pT3b disease in the contemporary era. MATERIALS AND METHODS The institutional radical prostatectomy database (1982 to 2010) of 18,505 men was queried and 989 with pT3b tumors were id...

conclusions lidocaine-meperidine-diltiazem gel provides significantly better pain control than lidocaine-diltiazem gel and lidocaine gel alone during transrectal ultrasound guided prostate biopsy and probe insertion. this mixture gel is safe, easy to administer and well accepted by patients. results the mean of visual analog pain scale was 4.5 in group a, 3.5 in group b, and 2.0 in group c duri...

OBJECTIVES To establish a formula that estimates tumor volume in localized prostate cancer based on serum prostate specific antigen levels. One of the main prognostic variables in localized prostate cancer is tumor volume, which can be precisely defined only after prostate extirpation. The present study defines a simple method that allows for estimation of tumor volume before treatment, which c...

BACKGROUND Female urethral carcinoma is a very rare disease that accounts for 0.02% of malignant diseases in female patients. CASE PRESENTATION A 70-year-old Asian Japanese woman with a urethral tumor was referred to our hospital to undergo further examination. Biopsy specimens showed urethral adenocarcinoma that was positive for prostate-specific antigen. Her serum prostate-specific antigen ...

The following information was prepared and distributed as a handout at the ACLI Medical Section’s June 12, 1993, Tumor Marker Committee meeting in Boca Raton, Florida. The information was subsequently published in the September/October 1993 issue of Lincoln National Reinsurance Medical Resource (R) and is reprinted here with permission from Lincoln National Life Reinsurance Company. (Copyright ...

A free screening clinic for cancer of the prostate was held in Madison County, New York, in September 1990, in conjunction with Prostate Cancer Awareness Week, a program of the Prostate Cancer Educational Council. Serum prostate specific antigen and digital rectal examination were used to screen 565 men. The two tests were equally effective in identifying patients with carcinoma. Of 118 patient...