OBJECTIVE To evaluate if prostate specific antigen test attains validity standards required for screening in view of recent prostate cancer screening trial results. DESIGN Case-control study nested in longitudinal cohort. SETTING Västerbotten Intervention Project cohort, Umeå, Sweden. PARTICIPANTS 540 cases and 1034 controls matched for age and date of blood draw. MAIN OUTCOME MEASURE V...

The following information was prepared and distributed as a handout at the ACLI Medical Section’s June 12, 1993, Tumor Marker Committee meeting in Boca Raton, Florida. The information was subsequently published in the September/October 1993 issue of Lincoln National Reinsurance Medical Resource (R) and is reprinted here with permission from Lincoln National Life Reinsurance Company. (Copyright ...

A free screening clinic for cancer of the prostate was held in Madison County, New York, in September 1990, in conjunction with Prostate Cancer Awareness Week, a program of the Prostate Cancer Educational Council. Serum prostate specific antigen and digital rectal examination were used to screen 565 men. The two tests were equally effective in identifying patients with carcinoma. Of 118 patient...

To the Editor. Oesterling published an extensive review on the clinical usefulness of prostate specific antigen (PSA) [1] and updated the study in 1994. Although both reviews cover adequately clinical and basic aspects of PSA in the area of urology, important new information on PSA was not mentioned. We with to supplement the recent review with articles published in 1994 showing that PSA can no...

Percent free prostatic-specific antigen (%fPSA) has been introduced as a tool to avoid unnecessary biopsies in patients with a serum PSA level of 4.0-10.0 ng ml-1 , however, it remains controversial whether %fPSA is effective in PSA range of 10.1-20.0 ng ml-1 in both Chinese and Western population. In this study, the diagnostic performance of %fPSA and serum PSA in predicting prostate cancer (P...

PURPOSE Little is known about the effects of literacy levels on prostate cancer screening. This study evaluates the association between literacy, compliance with screening, and biopsy findings in a large Brazilian screening study. MATERIALS AND METHODS We analyzed 17,571 men screened for PCa with digital rectal examination (DRE) and total and free prostate-specific antigen (PSA) from January ...