Proteases are one of the largest and best-characterized families of enzymes in the human proteome. Unfortunately, the understanding of protease function in the context of complex proteolytic cascades remains in its infancy. One major reason for this gap in understanding is the lack of technologies that allow direct assessment of protease activity. We report here an optimized solid-phase synthes...

Final instar larvae of S. mauritia treated topically on day 0, 1, 2 and day 3 with a daily dose of 20 microg juvenile hormone analogue (JHA) showed an increase in most of the nutritional parameters such as approximate digestibility, efficiency of conversion of ingested food, consumption index and growth rate. Also, the activities of digestive enzymes amylase, invertase, trehalase and protease i...

Proteases, also known as proteolytic enzymes, are enzymes that catalyze the breakdown of proteins by hydrolysis of peptide bonds. Earlier proteases were considered as only protein degrading enzymes, however now dramatically the view has changed. Proteases are extremely important signalling molecules that are involved in numerous vital processes like apoptosis, cell growth and activation, adhesi...

The Actinomycetes are gram-positive, unicellular bacteria that grow in a typical filamentous manner on solid substrates and may synthesis wide range of secondary metabolites, including enzymes. Proteases universally present enzymes catalyze hydrolytic processes break down protein molecules into peptides amino acids. protease enzyme is used food detergent industries. goal the current investigati...

BACKGROUND The microbial cell factory Bacillus subtilis is a popular industrial platform for high-level production of secreted technical enzymes. Nonetheless, the effective secretion of particular heterologous enzymes remains challenging. Over the past decades various studies have tackled this problem, and major improvements were achieved by optimizing signal peptides or removing proteases invo...

Human immunodeficiency virus type 1 (HIV-1) protease optimally catalyzes in the pH range of 4-6 in contrast to nearly all of the other eukaryotic aspartic proteases, which catalyze best in the pH range of 2-4. A possible structural reason for the higher optimal pH of HIV-1 protease is the absence of a hydrogen bond to the carboxyl group of active-site Asp25, which is nearly universally present ...

Activities of mitochondrial enzymes in blood cells from 69 patients with primary sideroblastic anemia were determined to elucidate the pathogenesis of the disease. In erythroblasts of patients with primary acquired type the activities of both delta-aminolevulinic acid synthetase and mitochondrial serine protease were inevitably decreased. The susceptibility to the protease of apo-delta-aminolev...

Snake venom contains various bioactive proteins and peptides, of which enzymes make up a significant portion. Desert Black Cobra (Walterinnesia morgani) is venomous snake distributed mainly in the Middle East including southeastern Türkiye. The aim present study to investigate key enzyme activities protein profile W. morgani originating from Sanliurfa province. After determination content, samp...

BOBOEV, A., A. HASANOV, L. YOTOVA and H. HASANOV, 2012. Antioxidant activity of peptides obtained from wheat and cottonseed proteins. Bulg. J. Agric. Sci., 18: 103-111 Enzymatic hydrolysis of various wheat proteins and cottonseed with acid (Prolive PAC 30L “EnzymeBioProduct” Ltd, Russia) and neutral proteases (Neutrase, ‘’Novozymes’’, Denmark) was studied. The antioxidant properties of the prod...

In other papers ofthis series (Holden, Pirie & Tracey, 1950; Holden, 1950a, b) the effects of a number of polysaccharases on leaf fibre are described. The only polysaccharase recognized in tobacco leaves in significant quantity is amylase (Frankenburg, 1946), and even this is not present in sufficient quantity to effect complete removal of starch on repeated prolonged incubation. It is convenie...