نتایج جستجو برای: protective antigens
تعداد نتایج: 225132 فیلتر نتایج به سال:
Infants and very young children are poor responders to polysaccharide antigens (1-4) and fail to make protective antibody responses to a number of polysaccharide-containing vaccines including the 23-valent pneumococcal vaccine (2, 5) currently used to immunize adults (6). One way to attempt immunization of children against encapsulated bacteria is to modify the capsular polysaccharides so that ...
The development of an antigen schema for Pseudomonas aeruginosa based on challenge protection in mice as distinguished from serological tests in vitro was described. For 342 cultures, seven groups of cross-protective homogeneity were defined.
BACKGROUND Partial protective efficacy lasting up to 43 months after vaccination with the RTS,S malaria vaccine has been reported in one cohort (C1) of a Phase IIb trial in Mozambique, but waning efficacy was observed in a smaller contemporaneous cohort (C2). We hypothesized that low dose exposure to asexual stage parasites resulting from partial pre-erythrocytic protection afforded by RTS,S ma...
Pasteurella multocida is an important pathogen that leads to a range of diseases that have severe economic consequences on cattle production. In order to develop an effective cross‑protective component vaccine, an immunoproteomics approach was used to analyze outer membrane proteins (OMPs) of the P. multocida serotype A, B and F strains. Candidate antigen molecules from the whole genome were sc...
Burkholderia are highly evolved Gram-negative bacteria that primarily infect solipeds but are transmitted to humans by ingestion and cutaneous or aerosol exposures. Heightened concern over human infections of Burkholderia mallei and the very closely related species B. pseudomallei is due to the pathogens' proven effectiveness as bioweapons, and to the increased potential for natural opportunist...
This study was performed in order to define Schistosoma mansoni antigens able to function as modulator agents in BALB/c mice granulomatous hypersensitivity to parasite egg. The antigens P-24, P-35 and P-97 were purified by affinity chromatography from a fraction of S. mansoni adult worm antigenic preparation, denominated PIII, involved in the inhibition of granulomatous response to eggs. Immuni...
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