Microbial Transglutaminase (MTgase) shows a wide specificity of action in its ability to interact with proteins from different families. Previous experimental data (in collaboration with BIOKER, POLARIS, Pula, Italy) demonstrated that MTGase interacts and transglutaminates the Granulocyte-Colony-StimulatingFactor (GCSF) at residue Q135. In this work this interaction is investigated through the ...

introduction: regulators of g-protein signaling protein negatively control g protein -coupled receptor signaling duration by accelerating gα subunit guanosine triphosphate hydrolysis. since regulator of g-protein signaling4 has an important role in modulating morphine effects at the cellular level and the exact mechanism(s) of adrenalectomy-induced morphine sensitization have not been fully cla...