Emetine is a potent inhibitor of protein synthesis in sea urchin embryos. At a concentration of the drug that rapidly inhibits protein synthesis in blastulae by 95%, uridine incorporation into RNA continues for more than 1 hr and presumptive histone messenger RNA is synthesized and transported into the cytoplasm where it is apparently associated with polyribosomes. Possible explanations of this...

Rumen is a persistent and specific ecosystem consists of bacteria, protozoa and fungus where feed fermentation takes place in it. Produced Hydrogen in rumen can be used in the synthesis of the volatile fatty acids and the microbial protein and its excess would be eliminated through the production of Methane by methanogenesis. Nutritionists have tried to find ways to decrease loss and energy and...

Herein, recent developments in the production and reactivity of distonic radical anions are reviewed. Known and potential reactions utilizing both the radical and anion centers are highlighted. While work has revealed new distonic radical anion species, limited effort has been to apply them to complex molecule synthesis. Through the development of new photoinduced electron transfer reagents, di...

The plasma concentration and hepatic synthesis rates of albumin, transthyretin, very low-density lipoprotein apolipoprotein B-100 (VLDL-apoB-100), high-density lipoprotein apolipoprotein A-1, fibrinogen, alpha1-antitrypsin, and haptoglobin were measured in six normal adults before and after consuming a protein intake of 0.6 g. kg body wt(-1). day(-1) for 7 days. The synthesis of hepatic protein...

Influenza virus unspliced NS1 mRNA, like retroviral pre-mRNAs, is efficiently exported from the nucleus and translated in the cytoplasm of infected cells. With human immunodeficiency virus (HIV), the transport of viral pre-mRNAs is facilitated by the viral Rev protein. We tested the possibility that the influenza virus NS1 protein, a nuclear protein that is encoded by unspliced NS1 mRNA, has th...

Influenza virus unspliced NSl mRNA, like retroviral pre-mRNAs, is efficiently exported from the nucleus and translated in the cytoplasm of infected cells. With human immunodeficiency virus (HIV), the transport of viral pre-mRNAs is facilitated by the viral Rev protein. We tested the possibility that the influenza virus NSl protein, a nuclear protein that is encoded by unspliced NSl mRNA, has th...

the cannabinoidergic system acquired a reputation as the most abundant g-protein coupled receptor in the cns that acts as retrograde modulator of neurotransmitter release. recently, endocannabinoids (ecbs) have been highlighted as neurodevelopmental signaling cues that exert a regulatory role in brain development. the interruption in ecb system elements (including receptors and enzymes of synth...