There are probably no biological samples that did more to spur interest in proteomics than serum and plasma. The belief was comparing the proteomes of these obtained from healthy disease-affected individuals would lead biomarkers could be used diagnose conditions such as cancer. While continuing development mass spectrometers with greater sensitivity resolution has been invaluable, invention st...

saliva is multifunctional; it is a lubricant for speech, aide for food digestion, and protective against microorganisms. it is voluntarily accessible, composed of proteins and electrolytes, and is ideal for the early detection of a wide range of diseases. because of a complex protein mixture, saliva proteomics has the potential to be a novel approach in the search for protein biomarkers. most s...

This review is devoted to the consideration of mass spectrometric platforms as applied omics sciences. The most significant attention paid related life sciences (genomics, proteomics, meta-bolomics, lipidomics, glycomics, plantomics, etc.). Mass approaches solving problems petroleomics, polymeromics, foodomics, humeomics, and exosomics, inorganic sciences, are also discussed. comparatively pres...

This Special Issue entitled “Application of Proteomics and Enzyme Technologies in Foods” explores the latest progress perspectives on development application enzyme technologies, proteomics, bioprocessing context food science [...]

Wnt signalling is a critical developmental pathway and associated aberrant signaling drives oncogenesis including colorectal bone cancer. β-catenin, central protein forms range of protein-protein interactions(PPIs), fundamental to driving the transcription oncogenes inducing proliferation tumour formation. To further elucidate these interactions, we have sought i) identify inhibitors β-catenin ...

The plant system is a highly dynamic structure on all molecular levels, transcripts, proteins, and metabolites. Thus, protein analysis has to cope with a highly dynamic range of concentrations. A severe problem is the detection of low-abundance proteins in the presence of housekeeping proteins. Basically three approaches are facilitated to measure protein abundance in a comprehensive manner: 2D...

The global profiling of the whole protein complement of the genome expressed in a particular cell or organ, or in plasma or serum, makes it possible to identify biomarkers that respond to alterations in diet or to treatment, and that may have predictive value for the modelling of biological processes. Proteomics has not yet been applied on a large scale in nutritional studies, yet it has advant...