BACKGROUND Echinococcus granulosus (EG) complex, the cause of cystic echinococcosis (CE), infects humans and several other animal species worldwide and hence the disease is of public health importance. Ten genetic variants, or genotypes designated as (G1-G10), are distributed worldwide based on genetic diversity. The objective of this study was to provide some sequence data and phylogeny of EG ...

Gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) were employed to determine the chemical composition of the essential oil (EO) from aromatic water (AW) of Zataria multiflora. Thymol (66.9%), carvacrol (15.2%), and carvone (7.3%) were found to be the major EO constituents. Eighty laboratory BALB/c mice were infected intraperitoneally by injection of 1,500 viable protoscol...

Despite the establishment of extensive and successful control programmes in some countries or regions, Echinococcus granulosus still has a very wide geographical distribution. Mature E. granulosus (n = 120) obtained from Parasitology Department, School of Veterinary Medicine, Ferdowsi University of Mashhad (Iran). Soluble protein of whole body of parasite was prepared by freeze-thawing in liqui...

We conducted this study to determine the level of immunity after vaccination of lambs with whole bodyEchinococcus granulosus. To do so, 200 mature E. granulosus parasites, which were kept in 10% formalinefor 8 months, were obtained from the Department of Parasitology, School of Veterinary Medicine, FerdowsiUniversity of Mashhad. The soluble protein of the parasite was prepared. The sample was h...

echinococcosis is one of the world’s relevant zoonoses, affecting both humans and their domestic animals and caused by infection with the metacestode stage of the dog tapeworm, echinococcus granulosus. in the present study, twenty mice were randomly divided into 4 groups of 5. each mouse in groups 1, 2 and 3 was immunized with 100 μg of hydatid cyst fluid protein, protoscolex and adult worms of...

sheep is one of the important hosts for hydatidosis in iran as a hyperendemic region worldwide. in the present study, the efficacy of counter immuno-electerophoresis (cie) and pcr tests to detect sheep hydatid cyst infection was carried out. for this, soluble antigen was provided using hydatid cyst fluids (hcfs). blood sera were taken from a total number of 100 slaughtered sheep. cie analysis w...

In current study, a few sheep cystic livers and lungs were obtained from Mashhad slaughter house and protoscolex were separated aseptically. Thirty 6-week-old Swiss mice were divided into 5 groups and two thousands of live protoscolices were inoculated intrapritoaneally in each mouse. In group 1 and 2 (prophylactic groups), mice were given 150 mg/kg of oral albendazole and mebendazole for 10 da...

objective(s): there are several scolicidal agents for inactivation of hydatid cyst protoscolices during surgery, but most of them are associated with adverse side effects such as sclerosing cholangitis and liver necrosis. the present study was aimed to evaluate scolicidal effects of various extracts of nigella sativa seeds againstprotoscoleces of hydatid cyst in an in vitro model. materials and...