BACKGROUND Chronic suppurative otitis media (CSOM) is a prevailing and notorious infection in developing countries causing serious local damage and threatening complications. Early and effective treatment based on the knowledge of causing micro organisms and their sensitivity results in good clinical recovery and prevents from damage and complications. Pseudomonas aeruginosa is most common path...

The antibacterial activity of ethanolic extracts of Ziziphus spina-christi leaves were examined using agar disc diffusion method against five bacteria (Streptococcus feacalis, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa). These extracts had inhibitory activity at various stages of germination;1st stage has inhibitory activity of 22 mm against Strept...

the broad consumption of antibiotics such as fluoroquinolones and the genetic adaption of opportunistic pathogenic bacteria including pseudomonas aeruginosa , has led to develop of floroquinolone-resistant strains of pseudomonas aeruginosa . thus, the aim of the present study is to reveal the types of hot spot mutations occurring in selected dna gyrase subunit a gene in fluoroquinolone-resistan...

Pseudomonas aeruginosa, an important opportunistic pathogen causing a wide range of acute and chronic infections.The present study was undertaken to detect the Metallo β lactamase in isolated of Pseudomonas aeruginosa which was isolated from wound infection and evaluated their susceptibility patterns.The presence of the MBL enzyme was detected by phenotypic confirmatiory tests are IMIPENEM-EDTA...

OBJECTIVE To find out the frequency and susceptibility pattern of multi-drug resistant (MDR) Pseudomonas aeruginosa in clinical specimens. STUDY DESIGN Cross-sectional observational study. PLACE AND DURATION OF STUDY Department of Microbiology, Army Medical College, National University of Sciences and Technology (NUST), Rawalpindi, from January to September 2010. METHODOLOGY Routine clini...

The aim of the present study was to determine the sensitivity pattern of clinical isolates of otitis media. During the last few decades, the occurrence of otitis media seems to have been rising probably because of prevalence of multidrug-resistant Pseudomonas aeruginosa and β-lactamase producing Staphylococcus aureus in the pathogenesis of otitis media. Pseudomonas aeruginosa and Staphylococcus...

Antibodies to Pseudomonas aeruginosa from 10 cystic fibrosis patients with chronic P. aeruginosa lung infections were quantitatively and qualitatively analyzed. The development of specific antibodies in patient serum was evaluated in a longitudinal study (1972 to 1987). The concentrations and specificities of immunoglobulin G (IgG) and IgM antibodies to purified lipopolysaccharides (LPS) from c...

Inflammasome signaling can contribute to host innate immune defense against bacterial pathogens such as Pseudomonas aeruginosa. However, bacterial evasion of host inflammasome activation is still poorly elucidated. Quorum sensing (QS) is a bacterial communication mechanism that promotes coordinated adaptation by triggering expression of a wide range of genes. QS is thought to strongly contribut...