The effects of physosti~ine, nicotine and scopolamine were studied on the activity of single lateral geniculate neurons in the acute cat. Most of the lateral geniculate neurons selected were P-cells. These increased their responses to ipsilateral optic tract and midbrain reticular formation stimulation. Nicotine and physostigmine in doses of 25 pg/kg i.v. significantly increased the spontaneous...

OBJECTIVE To investigate regeneration of the distal facial nerve following nerve grafting within the tympanic segment with geniculate ganglion preservation or dissection. DESIGN Randomized controlled trial. SUBJECTS Twenty-three adult New Zealand albino rabbits were used in this study. INTERVENTIONS A 2-mm tympanic segment of the facial nerve was removed, and the greater auricular nerve w...

Brain-derived neurotrophic factor and neurotrophin-4 are required for normal taste bud development. Although these neurotrophins normally function via the tyrosine kinase receptor, trkB, they also bind to the pan-neurotrophin receptor, p75. The goal of the present study was to determine whether the p75 receptor is required for the development or maintenance of a full complement of adult taste b...

Taste function requires neural circuits to transmit gustatory information from taste receptor cells in taste buds, via afferent nerves to the soma of ganglion neurons, and through central ganglion processes into the brainstem. During initial formation, the sensory ganglion neurons have a key situation in establishing receptive fields by extending neurites bidirectionally, to the peripheral tast...

We investigated the changes in NADPH-diaphorase staining that occur in the lateral geniculate nucleus of cats following rearing with monocular lid suture. This staining allows visualization of the synthesizing enzyme of nitric oxide, a neuromodulator associated with plasticity. In the lateral geniculate nucleus of normally reared cats, NADPH-diaphorase exclusively labels the axons and terminals...

Lateral geniculate nucleus Retinotopic organization Vision Abstract A comparative survey shows that lamination is a basic feature of the mammalian dorsal lateral geniculate nucleus. Relay laminae receive input from the retina, project to the cerebral cortex and represent a complete hemiretina. They are distinguished from incomplete layers or leaflets and from groups of cells for which retinal c...

t\BSTRACT A cylindrical cellular discontinuity commonly occurs in lateral geniculate layers that are Innervated by the contralateral eye. Such a disconti ­ nuity has been found In a variety of mammalian species, including carnivores, primates, a rodent and a marsupial. Electrophyslological evidence obtained from some of these species shows ulat the discontinuity corresponds to the blind spot. I...

Objectives Discussion of a rare case of angioleiomyoma involving the geniculate ganglion and the intratemporal facial nerve segment and its surgical treatment. Design Case report. Setting Presence of an expansive lesion englobing the geniculate ganglion without any lesion to the cerebellopontine angle. Participants A 45-year-old man with a grade III facial paralysis according to the House-Brack...

The effects of chronic administration of efavirenz commonly used as part of highly active antiretroviral therapy (HAART) for the treatment of Human Immunodeficiency Virus (HIV) type-1 therapy on the nissl substance of the intracranial visual relay centres namely the superior colliculus and lateral geniculate body of adult wistar rats were carefully studied. The rats of both sexes (n=20), with a...

PURPOSE Retinoblastoma is a rare eye cancer that generally occurs before 5 years of age and often results in enucleation (surgical removal) of the cancerous eye. In the present study, we sought to determine the consequences of early monocular enucleation on the morphological development of the anterior visual pathway including the optic chiasm and lateral geniculate nucleus. METHODS A group o...