BACKGROUND Psoriasis is a chronic inflammatory skin disease that affects up to 5.5% of world population and is associated with erectile dysfunction (ED). Aim of the present study was to investigate impact of metabolic syndrome (MetS) on association between psoriasis and ED as well as to improve our understanding of this association via studying other possible causes of ED such as psychological ...

BACKGROUND AND OBJECTIVES The nails are affected in a substantial number of patients with psoriasis. Nevertheless, few epidemiological studies have reported the characteristics of patients with nail psoriasis. Here we describe the epidemiology of nail psoriasis and the main characteristics of affected patients. PATIENTS AND METHODS We undertook a prospective case-control study at Hospital Uni...

Psoriatic arthritis (PsA) is a chronic inflammatory arthritis that can cause severe joint deformities and disability. The expected prevalence of inflammatory arthritis among patients with psoriasis has varied from 7% to 40%. Early diagnosis and treatment of PsA is recommended to discourage from disease associated disability and breakdown of work place efficiency. The epidemiological studies are...

1. Rapp SR, Feldman SR, Exum ML, Fleischer AB Jr, Reboussin DM. Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol 1999;41:401-7. 2. Reed WB, Becker SW, Rhode, Heiskell CL. Psoriasis and arthritis: A clinicopathological study. Arch Dermatol 1961;83:541-8. 3. Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in pat...

STUDY DESIGN The Oswestry Disability Index (ODI) has become one of the principal condition-specific outcome measures used in the management of spinal disorders. This review is based on publications using the ODI identified from the authors' personal databases, the Science Citation Index, and hand searches of Spine and current textbooks of spinal disorders. OBJECTIVES To review the versions of...

BACKGROUND Palmoplantar pustulosis (PPP) is a recalcitrant chronic inflammatory skin disease. Data relevant for the medical care of patients with PPP are scarce. Thus, the aim of this work was to investigate the disease burden, clinical characteristics, and comorbidity of PPP patients in Germany. PATIENTS AND METHODS PPP patients were examined in a crosssectional study at seven specialized ps...

OBJECTIVE To evaluate the safety and efficacy of long-term treatment of psoriasis with etanercept, 50 mg twice weekly. DESIGN, SETTING, AND PATIENTS A phase 3, randomized, double-blind trial with an open-label extension. A total of 618 adult patients with moderate to severe plaque psoriasis were studied at 39 medical centers in the United States and Canada from May 23, 2003, through June 22, ...