The electron microscopic alterations of the alveolar septum in advanced hemodynamic and alloxan-induced pulmonary edema were compared. Pulmonary edema was produced in anesthetized dogs by means of increased left atrial pressure and hemodilution and by alloxan administration. Sections of pulmonary tissue from these dogs and similarly anesthetized controls were processed for and examined by light...

Pulmonary alveolar proteinosis (PAP) is a progressive lung disease characterized by accumulated surfactant-like lipoproteinaceous material in the alveoli and distal bronchioles. This accumulation is the result of impaired clearance by alveolar macrophages. PAP has been described in 11 solid organ transplant recipients, 9 of whom were treated with mammalian target of rapamycin inhibitors. We rep...

Background: In Covid-19 the virus infects respiratory tract in human. When lung tissue becomes diseased, walls and lining of alveoli capillaries are damaged. At this point compliance ventilation decrease. Pulmonary surfactant that is produced dispersed into alveolar space, has a significant role understanding how heavily covid-19 interferes cells. The importance pulmonary to lower surface tensi...

Chronic obstructive pulmonary disease, which by this point we define COPD, is understood as a situation of progressive airflow limitation, sometimes reversible, whose pathogenetic mechanisms responsible are to be attributed, on the one hand, to the progressive obstruction of the central and peripheral airways, with structural modification of their histological status and, secondly, to a progres...

relatively small drop in intrapleural pressure or change in the configuration of the hilum associated with a deep breath can have on perfusion, and second, the implication that this has on the assumption that inspired lS3xenon in the lung is necessarily in the alveoli rather than in the conducting airways. The xenon that diffused from the pulmonary capillaries in the left lung had no significan...

BACKGROUND Restrictive atrial septal defect (ASD) (including intact atrial septum [IAS]) has been reported to be a risk factor that negatively impacts survival in hypoplastic left heart syndrome (HLHS). Although lymphangiectasia and "arterialization" of the veins of the lung in HLHS with restrictive ASD have been reported, they cannot fully explain the high mortality. We have introduced a new m...

Abstract Polygonum cuspidatum (PC) extract has effect on silica-induced pulmonary fibrosis. This study aimed to explore the anti-pulmonary-fibrosis effects and mechanism of PC. Sprague–Dawley rat model was constructed by inhalation silicon dioxide suspension through tracheal intubation method. And histopathological examination showed that PC inhibited inflammatory cell infiltration, fibrous col...

This article is available online at http://www.jlr.org Pulmonary surfactant is a complex of phospholipids ( 90%) and proteins ( 10%) that reduces the surface tension in the alveoli of the lung ( 1, 2 ). Pulmonary surfactant is crucial for normal breathing and its defi ciency leads to fatal respiratory distress syndromes ( 3 ). The major phospholipids in pulmonary surfactant are phosphatidylcho...