The calculated systolic, diastolic and mean pulmonary artery pressure, the ratio of sizes right left ventricles heart, eccentricity index ventricle, systolic excursion fibrous ring tricuspid valve, movement myocardium at level valve area atrium are main echocardiographic indicators for assessing idiopathic similar forms hypertension according to current Russian, Eurasian European guidelines in ...

Pulmonary hypertension is a hemodynamic and pathophysiological condition defined as an increase in mean pulmonary pressure more than or equal to 25 mm Hg. Risk stratification and prognostic evaluation in patients with pulmonary hypertension are complex and require multiple investigations. There is a lack of consensus on factors that predict mortality and prognosis in patients with pulmonary art...

The effects ofpulmonary hypertension on cardiopulmonary function were investigated by ventilatory, haemodynamic, and metabolic studies at rest and during exercise. The studies were carried out in 12 patients with primary, thromboembolic, or residual pulmonary hypertension after surgical closure of intracardiac defects, and in II patients with pulmonary hypertension secondary to obstructive lung...

The phenotype and outcome of severe pulmonary hypertension in chronic obstructive pulmonary disease (COPD) is described in small numbers, and predictors of survival are unknown. Data was retrieved for 101 consecutive, treatment-naïve cases of pulmonary hypertension in COPD. Mean ± SD follow-up was 2.3 ± 1.9 years. 59 patients with COPD and severe pulmonary hypertension, defined by catheter mean...

Pulmonary hypertension is uncommonly associated with portal hypertension. The current approach for the management of pulmonary hypertension involves the use of vasodilators in patients who show vascular responsiveness during an acute challenge. Since the association of portal hypertension with pulmonary hypertension is very seldomly presented, its optimal therapy has not been defined. Moreover,...

The regulation of pulmonary vascular tone is a complex process and represents a balance between constrictor and dilator influences. In pulmonary hypertension, whether caused by hypoxia or flowand pressure-induced remodeling, the balance is tilted predominantly toward vasoconstriction. Despite decades of research, the initiating events in most patients with primary pulmonary hypertension remain ...

RATIONALE Severe pulmonary hypertension occurs occasionally in patients with chronic obstructive pulmonary disease (COPD), but no detailed description of these patients is available. OBJECTIVES To identify and characterize patients with COPD and severe pulmonary hypertension. METHODS Retrospective study of 27 patients with COPD with severe pulmonary hypertension (pulmonary artery mean press...