PURPOSE To investigate the amount of single-stranded DNA breaks in circulating leukocytes of primary open-angle glaucoma (POAG) patients. METHODS A comparative quantification of DNA breaks was performed in circulating leukocytes of POAG patients and healthy controls. The following groups of subjects were compared: (1) POAG patients having primary vascular dysregulation (PVD), (2) POAG patient...

Biocompatibility improvements for blood contacting materials are of increasing interest for implanted devices and interventional tools. The current study focuses on inorganic (titanium, titanium nitride, titanium oxide) as well as diamond-like carbon (DLC) coating materials on polymer surfaces (thermoplastic polyurethane), deposited by magnetron sputtering und pulsed laser deposition at room te...

BACKGROUND In patients with end-stage renal disease, peripheral vascular disease (PVD) is prevalent. We assessed the extent to which severity of PVD predicts mortality, hospitalizations and health-related quality of life (HRQOL) in hemodialysis (HD) patients enrolled in the Hemodialysis (HEMO) Study. METHODS We performed a subanalysis of the HEMO Study, a randomized controlled trial. Adjusted...

PVD and FLP sensory neurons envelope the body of the C. elegans adult with a highly branched network of thin sensory processes. Both PVD and FLP neurons are mechanosensors. PVD is known to mediate the response to high threshold mechanical stimuli. Thus PVD and FLP neurons are similar in both morphology and function to mammalian nociceptors. To better understand the function of these neurons we ...

The performance of coated inserts was described using Response Surface Methodology (RSM) when turning AISI 4340 alloy steel using single layer PVD and triple layer CVD coated inserts. Cutting tests were performed under dry cutting conditions so as to reduce the effects of cooling agents on the environment. Surface roughness (Ra) was the main response variable investigated. The experimental plan...

Environmental barrier coatings (EBCs) were developed to reduce the susceptibility of SiC-based composites rapid volatilization and surface recession that occurs in presence water vapor. Extensive research development has been performed on EBCs, their corresponding failure mechanisms under different environmental conditions. However, one key mechanism, solid particle erosion (SPE), not thoroughl...

Tribological components cost just a fraction of the whole spacecraft, but they often lead to failures that partially or completely disrupt spacecraft. Mechanical used in space applications have withstand extreme and severe environmental conditions such as very high low cryogenic temperatures, vacuum, corrosive elements radiation. MoS2 is most widely lubricating material applications. It possess...

Coexisted peripheral vascular disease (PVD: ankle/brachial pressure index A/PBI less than 0.75) or carotid artery disease (CTD: Brochenbrough's supraorbital Doppler flow analysis) were diagnosed by non-invasive testings, and correlated with clinical pictures and coronary backgrounds in 121 consecutive patients with confirmed coronary artery disease. PVD were found in 16.5%, CTD in 33.1% and bot...