A method using QuEChERS sample preparation and an Agilent 6490 Triple Quadrupole LC/MS has been developed that provides rapid and sub-parts per billion (ppb) detection of synthetic yohimbine and yohimbe bark extract in dietary supplements. Using the chromatographic separation of the diastereomers of yohimbine, the synthetic compound can be distinguished from the tree bark extract. An Agilent 65...

Undeclared synthetic substances or analogues of prescription drugs in herbal remedies can cause potential harm. The present work shows a simple but effective approach to unequivocally identify synthetic anorectic compounds in what is considered ‘natural’ herbal extracts, by exploiting Q-TOF LC/MS technology, with the help of the Agilent’s Forensic Accurate Mass Li-brary (Forensic PCDL AM), Agil...

Undeclared synthetic substances or analogues of prescription drugs in herbal remedies can cause potential harm. The present work shows a simple but effective approach to unequivocally identify synthetic anorectic compounds in what is considered ‘natural’ herbal extracts, by exploiting Q-TOF LC/MS technology, with the help of the Agilent’s Forensic Accurate Mass Li-brary (Forensic PCDL AM), Agil...

BACKGROUND Emerging technologies for rapid identification of microbes demonstrate a shift from traditional biochemical and molecular testing algorithms toward methods using mass spectrometry (MS) for the semiquantitative analysis of microbial proteins and genetic elements. This study was performed to assess the diagnostic accuracy of 2 such technologies, PCR-electrospray ionization (ESI)/MS and...

Smoking marijuana during pregnancy can cause health problems in the neonate. The detection of exposure can guide treatment to meet the short- and long-term medical and social needs. Umbilical cord tissue was analyzed for 11-nor-delta-9-carboxy-tetrahydrocannabinol (THC-COOH) by gas chromatography-mass spectrometry (GC-MS), and compared with ultra-sensitive enzyme-linked immunosorbent assay (ELI...

The growing market of herbal remedies worldwide could pose severe problems to consumers’ health due to the possible presence of potentially harmful, undeclared synthetic substances or analogues of prescription drugs. The present work shows a simple but effective approach to unequivocally identify synthetic anorectic compounds in allegedly ‘natural’ herbal extracts, by exploiting Q-TOF LC/MS tec...