Seismic analyses of methane hydrate data from the Blake Outer Ridge indicate high Pwave velocity and anomalously low S-wave velocity in sediments containing methane hydrates. In an attempt to explain this observed P-wave and S-wave velocity structure at the transition from gas to hydrates, the effect of different hydrate models on elastic moduli and velocities are explored. After construction o...

Background and Objective: Lipolysaccharide (LPS) is a large molecule isolated from bacteria such as the enterobacteriaceae family with a negative effect on memory and learning through disturbing the balance of free radicals and creating oxidative stress conditions. In this study, we evaluated  the effect of quercetin on oxidative stress and LPS-induced memory impairment in the rat. Materials a...

Hydrate phase equilibria for the binary CO2+water and CH4+water mixtures in silica gel pore of nominal diameters 6, 30, and 100 nm were measured and compared with the calculated results based on van der Waals and Platteeuw model. At a specific temperature, three-phase hydrate-water-vapor (HLV) equilibrium curves for pore hydrates were shifted to the higher-pressure condition depending on pore s...

Adhesion (cohesion) and agglomeration properties of gas hydrate particles have been a key to hydrate management in flow assurance in natural gas pipelines. Despite its importance, the relevant data in the area, such as the surface energy and the interfacial energy of gas hydrates with gas and/or water, are scarce; presumably due to the experimental difficulties involved in the measurements. Her...

A number of compounds were isolated from the medicinal plant Aster tataricus including shionone, epifriedelinol, quercetin, kaempferol, scopoletin, emodin, aurantiamide acetate and 1,7-dihydroxy-6-methyl-anthraquinone. The compounds were compared with regard to their ability in inhibiting hemolysis of rat erythrocytes induced by 2'-2' azobis (2-amidinopropane) dihydrochloride, lipid peroxidatio...

Alzheimer's disease (AD) is a neurodegenerative clinically characterized by progressive cognitive impairment. This work aimed to investigate the role of quercetin (Q) in treatment and protection AlCl3-induced AD rats through exploring molecular mechanisms underlying its neuroprotective therapeutic properties. In this study, male Wistar were allocated two experiments: experiment I (therapeutic e...

OBJECTIVE To investigate the protective effects of quercetin on cadmium-induced cytotoxicity in primary cultures of rat proximal tubular (rPT) cells. METHODS Primary cultures of rPT cells undergoing exponential growth were incubated with 1.0 μg/mL quercetin and/or cadmium (2.5, 5.0 μmol/L), in a serum-free medium at 37 °C at different time intervals. Commercial kits were used and flow cytomet...

OBJECTIVE In vitro, transglutaminase-2 (TG2)-mediated activation of the β-catenin signaling pathway is central in warfarin-induced calcification, warranting inquiry into the importance of this signaling axis as a target for preventive therapy of vascular calcification in vivo. METHODS AND RESULTS The adverse effects of warfarin-induced elastocalcinosis in a rat model include calcification of ...

In the present study, beneficial effect of leaves Ziziphus mauritiana on testosterone, estradiol, progesterone, LH hormones, blood glucose, and total cholesterol levels in experimentally induced polycystic ovaries female Sprague Dawley rats were evaluated. Letrozole was used to induce PCOS rats, clomiphene citrate as a standard control. This study carried out vivo 30 where group I received norm...

AIM The present study investigates synergistic effect of combination treatment of lycopene, quercetin and poloxamer188 in 3-nitropropionic acid (3-NP)-induced Huntington's disease (HD). MATERIALS AND METHODS Anxiety and depression were induced in male Wistar rat by intra-peritoneal administration of 3-NP (10 mg/kg) for 14 days. Body weight was assessed on day 1, 7 and 14, whereas locomotion, ...