The present study was undertaken to investigate the protective effects of saponin on a hypertensive target organ (the kidney) in spontaneously hypertensive rats (SHRs) and also to explore the effect of saponin on the renin-angiotensin-aldosterone system (RAAS). A total of 24, 14-week-old SHRs were randomly divided into three groups; the first was administered low-dose saponin, the second with h...

Adjuvant System AS01 is a liposome-based vaccine adjuvant containing 3-O-desacyl-4'-monophosphoryl lipid A and the saponin QS-21. AS01 has been selected for the clinical development of several candidate vaccines including the RTS,S malaria vaccine and the subunit glycoprotein E varicella zoster vaccine (both currently in phase III). Given the known immunostimulatory properties of MPL and QS-21,...

Saponins are a group of naturally occurring plant glycosides which possess a wide range of pharmacological properties, including anti-tumorigenic and antiviral activities. To investigate whether saponin has anti-hepatitis C virus (HCV) activity, we examined the effect of saponin on HCV replication. HCV replication was efficiently inhibited at a concentration of 10 µg/ml of saponin in cell cultu...

0. Introduction Phonological representations include sequences of featural specifications, pq. Two properties can be observed about such sequences: (i) for a sequence pq to be of significance for the phonology of a language, p must be perceptibly different than q; (ii) to produce a sequence pq, the articulators must start in the configuration for p and then change into the configuration for q. ...

ophiocoma erinaceus muller &troschel; (ophiocomidae) is part of the extensive group of echinoderm that contains bioactive metabolites. as, the anti cancer potential of brittle star saponin has not been reported against cervical cancer, the present study was conducted to evaluate the anticancer effect of extracted crude saponin. saponin extraction was conducted using conventional method such as ...

Saponin 1 is a triterpeniod saponin extracted from Anemone taipaiensis, a traditional Chinese medicine against rheumatism and phlebitis. It has also been shown to exhibit significant anti-tumor activity against human leukemia (HL-60 cells) and human hepatocellular carcinoma (Hep-G2 cells). Herein we investigated the effect of saponin 1 in human glioblastoma multiforme (GBM) U251MG and U87MG cel...

In this note the notion of interval-valued fuzzy QS-algebra (briefly, i-v fuzzy QS-algebra), as well as the i-v level and strong i-v level QS-subalgebra is introduced. Several theorems which determine the relationship between these notions and QS-subalgebras are stated and proved. The images and inverse images of i-v fuzzy QS-subalgebras are defined, and how the homomorphic images and inverse i...

Ophiocoma erinaceus Muller &Troschel (Ophiocomidae) is part of the extensive group of echinoderm that contains bioactive metabolites. As the anti cancer potential of brittle star saponin has not been reported against cervical cancer, the present study was conducted to evaluate the anticancer effect of extracted crude saponin. Saponin extraction was conducted using conventional method such as fr...

We consider here the so called s-Carleson measures with additive logarithmic terms in the unit disc, when 0 < s < 1 and we give many equivalent definitions. As applications, we characterize the pointwise multipliers on Qs and on its logarithmic counterpart Qs,log. Boundedness of the Cesaro operator on Qs and from Qs,log to Qs is considered as well.