We report here an examination of the effect of thioredoxin (TRX) on the secretion of growth hormone (GH) from rat anterior pituitary cells in vitro. Treatment of rat pituitary cells with growth hormone-releasing factor (GRF), but not GH, led to a significant increase in intracellular TRX protein levels. GRF, recombinant human TRX (rhTRX), and a combination thereof were all shown to induce immed...

The aim of this study is to compare and analyze the components of ground reaction force (GRF) relative to the foothold heights during downward step of 16-t truck. Adult males (n= 10) jumped downward from each 1st, 2nd, 3rd foothold step and driver's seat orderly using hand rail. Sampling rate of force components of 3 axis (medial-lateral [ML] GRF, anterior-posterior [AP] GRF, peak vertical forc...

The main aim of this paper is to connect R-Fuzzy sets and type-2 fuzzy sets, so as to provide a practical means to express complex uncertainty without the associated difficulty of a type-2 fuzzy set. The paper puts forward a significance measure, to provide a means for understanding the importance of the membership values contained within an R-fuzzy set. The pairing of an R-fuzzy set and the si...

The Colorful Carathéodory theorem by Bárány (1982) states that given d+1 sets of points in R, the convex hull of each containing the origin, there exists a simplex (called a ‘rainbow simplex’) with at most one point from each point set, which also contains the origin. Equivalently, either there is a hyperplane separating one of these d+ 1 sets of points from the origin, or there exists a rainbo...

Juhasz and van Mill denote by dis(X) the least cardinal of a cover of X by discrete subspaces. They show that dis(X) ≥ c (and hence the answer to Question 1.1 is positive) for any compact crowded hereditarily normal X. In fact, this follows from their stronger result that for such X, rs(X) + ls(X) ≥ c, where rs(X) (resp., ls(X)) is the least cardinal of a cover of X by right(resp., left)-separa...

BACKGROUND Flip-flops and sandals are popular choices of footwear due to their convenience. However, the effects of these types of footwear on lower extremity biomechanics are still poorly understood. Therefore, the objective of this study was to investigate differences in ground reaction force (GRF), center of pressure (COP) and lower extremity joint kinematic and kinetic variables during leve...

Proper nutritional status is critical for maintaining growth and metabolic function, playing an intimate role in neuroendocrine regulation. Leptin, the recently identified product of the obese gene, may very well be an integral signal which regulates neuroendocrine responses in times of food deprivation. The present study examines leptin's ability to regulate hormonal synthesis and secretion wi...

This article proposes a comprehensive investigation of the automatic classification of functional gait disorders based solely on ground reaction force (GRF) measurements. The aim of the study is twofold: (1) to investigate the suitability of stateof-the-art GRF parameterization techniques (representations) for the discrimination of functional gait disorders; and (2) to provide a first performan...

BACKGROUND Partial body weight support (BWS) systems have been broadly used with treadmills as a strategy for gait training of individuals with gait impairments. Considering that we usually walk on level ground and that BWS is achieved by altering the load on the plantar surface of the foot, it would be important to investigate some ground reaction force (GRF) parameters in healthy individuals ...

The literature contains some hypotheses regarding the most favorable ground reaction force (GRF) for sprint running and how it might be achieved. This study tested the relevance of these hypotheses to the acceleration phase of a sprint, using GRF impulse as the GRF variable of interest. Thirty-six athletes performed maximal-effort sprints from which video and GRF data were collected at the 16-m...