An attempt to find pharmacological therapies to treat stroke patients and minimize the extent of cell death has seen the failure of dozens of clinical trials. As a result, stroke/cerebral ischemia is the leading cause of lasting adult disability. Stroke-induced cell death occurs due to an excess release of glutamate. As a consequence to this, a compensatory increased release of GABA occurs that...

La pandemia del COVID-19 y las medidas de distanciamiento social han supuesto un impacto negativo en la salud mental. El objetivo principal es estudiar el papel resiliencia como factor protector, ante confinamiento COVID-19. muestra fue 179 participantes con una media edad 40,85 años (DE = 13,7). Los análisis indican que predice forma muy significativa bienestar psicológico estado ánimo protect...

The protective effects of Septilin (herbal extract) against radiation-induced damage in testis of male rats have been studied Animals were divided into four main groups: 1Control group, 2Septilin group (100mg/kg body weight/day). 3Irradiated group (4Gy gamma-radiation), 4Protected group in which animals (Male rats) were given Septilin orally (100mg/kg body weight/day) for two weeks before radia...

Clinical trials are in progress to evaluate radio- and chemoprotection by the aminothiol 2-[(3-aminopropyl)amino]ethanethiol-dihydrogen phosphate ester (WR-2721; amifostine). Phase II and III clinical studies have demonstrated that i.v. administered WR-2721 protects against the toxicities of cis-diamminedichloroplatinum (II) and cyclophosphamide. In preclinical murine studies, we have now furth...

Drug use was investigated in 3476 college and university students. The participants also filled out a set of personality questionnaires along with questions about relationships with peers, parents, and boy/girlfriend. Behavioral Activation was the best personality predictor of drug use. Peer and parent support decreased the strength of association between Behavioral Activation and drug use in f...