The use of improved technology has fostered increasing interest in hypofractionated radiation therapy for prostate cancer. There also is convincing evidence that an unusual aspect of prostate cancer radiobiology allow a different approach to dose escalation that is radiobiological in nature. The aim of this paper is to explain the rationale behind hypo fractionated high -dose intensity -modulat...

13 Wolff, S., and H. E. Luippold, "The Biochemical Aspects of Chromosome Rejoining," in Progress in Radiobiology, eds. J. S. Mitchell, B. E. Holmes, and C. L. Smith (Edinburgh: Oliver and Boyd, 1956), p. 217. 14 Beatty, A. V., and J. W. Beatty, Amer. Jour. Bot., 46, 317 (1959). 15 Thornton, N. C., Contrib. Boyce Thompson Inst., 5, 371 (1933). 16 Jackson, W. A., and N. T. Coleman, Plant and Soil...

A generalization of the well known critical volume NTCP model is proposed to take into account dependence of the functional subunits of irradiated organ (or tissue). A new statistical version of the CLT is established to analyze the corresponding random fields. AMS classification: 60F05, 62E20, 62G15, 62P10.

A double-mirror multilayer monochromator was developed for the purpose of irradiating live cell cultures at the Synchrotron Radiation Center, University of Wisconsin-Madison. The monochromator is designed for the soft x-ray region with photon energies between 270 and 2400 eV. Multilayer mirrors with 55 bilayers of W/C and a bilayer spacing of d = 3.0 nm are sputter deposited on Si substrates. B...

The relation between the site of energy deposition and the site of its biological action is an important question in radiobiology. Even at 77 degrees K, evidence is clear that these two sites must be separated since energy deposition is random but specific products are formed. Several processes that may contribute to this separation are: 1) hole migration and stabilization through deprotonat...

Department of Pharmacology, University of Arizona Medical Center, Tucson, Arizona 85724 fD. H. R.]; Division of Radiobiology and Biophysics, University of Virginia School of Medicine, CharlottesvÃ1⁄4le,Virginia 22901 ¡W.B. L., C. J. K., H, A. H.]; Baltimore Cancer Research Center, National Cancer Institute, Baltimore, Maryland 21211 [L. J. M., S. M. L.J; and Biochemistry Cancer Research, Howar...

or radiation sensitization in a murine model of total body irradiation Thomas A. Davis, Michael R. Landauer, Steven R. Mog, Michal Barshishat-Kupper, Stephen R. Zins, Mihret F. Amare, and Regina M. Day Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Md., USA; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Be...