نتایج جستجو برای: radium content

تعداد نتایج: 417502  

Journal: :Nature 1940

Journal: :Nature 1903

Journal: :BMJ 1933

Journal: :Nature 1905

Journal: :Nature 1913

2012
Álvaro Pinto Patricia Cruz

In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recent...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2017
O Sartor D Heinrich N Mariados M J Méndez Vidal D Keizman C Thellenberg Karlsson A Peer G Procopio S J Frank K Pulkkanen E Rosenbaum S Severi J M Trigo Perez V Wagner R Li L T Nordquist

Background Six radium-223 injections at 4-week intervals is indicated for patients with castration-resistant prostate cancer and symptomatic bone metastases. However, patients usually develop disease progression after initial treatment. This prospective phase I/II study assessed re-treatment safety and efficacy of up to six additional radium-223 injections. Patients and methods Patients had c...

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