Among randomized controlled trials (RCTs), trials for primary prevention require large samples and long follow-up to obtain a high-quality outcome; therefore the recruitment process and the drop-out rates largely dictate the adequacy of the results. We are conducting a Phase III trial on persons with metabolic syndrome to test the hypothesis that comprehensive lifestyle changes and/or metformin...

OBJECTIVE To determine the effectiveness of a parent health report on fruit and vegetable consumption among preschoolers and kindergarteners. DESIGN Pre-post open design trial and a randomized controlled trial. SETTING A university-sponsored preschool and kindergarten. PARTICIPANTS A total of 63 parents of preschool and kindergarten students participated in the pre-post open design trial ...

Objectives: To evaluate the effectiveness of an interprofessional enhanced recovery after surgery (ERAS) program in patients undergoing minimally invasive heart valve procedures comparison to standard treatment a bicentric randomized controlled trial.

article: SWEAT2 study: effectiveness of trunk training on muscle activity after stroke. A randomized controlled trial - European Journal Physical and Rehabilitation Medicine 2021 August;57(4):485-94 Minerva Medica Journals

BACKGROUND Hepatic resection is still associated with significant morbidity. Although the period of parenchymal transection presents a crucial step during the operation, uncertainty persists regarding the optimal technique of transection. It was the aim of the present randomized controlled trial to evaluate the efficacy and safety of hepatic resection using the technique of stapler hepatectomy ...

Citation: Kulason K, Nouchi R, Hoshikawa Y, Noda M, Okada Y and Kawashima R (2018) The Beneficial Effects of Cognitive Training With Simple Calculation and Reading Aloud (SCRA) in the Elderly Postoperative Population: A Pilot Randomized Controlled Trial. Front. Aging Neurosci. 10:68. doi: 10.3389/fnagi.2018.00068 The Beneficial Effects of Cognitive Training With Simple Calculation and Reading A...