We have measured the concentration of cartilage-derived retinoic-acid-sensitive protein (CD-RAP) in synovial fluid (SF) from the knees of 49 patients with osteoarthritis (OA) and 79 with rheumatoid arthritis (RA) in order to investigate the correlation between the type of joint disease and level of CD-RAP. The mean concentration of CD-RAP in synovial fluid was significantly higher in OA than in...

Right atrial pressure (RAP) may become substantially elevated during heart failure and has been reported to reduce collateral flow to the ischemic myocardium of isolated hearts. The effect of elevated RAP on blood flow to collateral-dependent and normal myocardium of in situ hearts was studied in 20 open-chest anesthetized dogs with acute occlusion of the left anterior descending coronary arter...

We show that cell lines derived from childhood alveolar rhabdomyosarcoma (RMS) are very sensitive to the growth-inhibitory effects of the immunosuppressive agent rapamycin (RAP), compared to other human cell lines (50% inhibitory concentration range of 0.1-8 ng/ml, compared to 1280 to > 10,000 ng/ml). Our data suggest that the sensitivity of RMS lines is due to RAP inhibition of insulin-like gr...

Many applications of virtual agents, including those in healthcare and education, require engaging users in dozens or hundreds of interactions over long periods of time. In this effort, we are developing conversational agents to engage young adults in longitudinal lifestyle health behavior change interventions. Hip-hop and rap are one of the most popular genres of music among our stakeholders, ...

Reclaimed asphalt pavement (RAP) arises from the demolition of road layers. The Optimal Recycling Asphalt Pavements Project concerns cold recycling 100 % RAP without binder addition in base and subbase layers low-traffic roads. In this context, a test program was performed with Rhine region materials to evaluate impact mastic coating untreated RAP. A source reclaimed asphalts 4.4 bitumen is tes...

CA), and RAP (made as a recombinant fusion protein with glutathione S-transferase), as described in our original study.1 Briefly, 3 groups were tested: (1) a control group received 40 mL/kg buffer followed 15 minutes later by a second injection of 20 mL/kg buffer (n 5 11); (2) the rFVIII group received 40 mL/kg buffer followed by 200 U/kg human rFVIII in a volume of 20 mL/kg (n 5 15); (3) the R...

How do music therapists experience themselves in clinical improvisation in music therapy? The aim of this inter-disciplinary study is to show how music therapists describe and experience the life-world of the self in clinical improvisation through phenomenological investigation. Informed by sociological social psychological theory proposing that the self develops in social discourses, this stud...

Although quantifiable assessment of the singing voice is now commonplace, research on young (child and adolescent) voices is still in its infancy. There is still insufficient data on young people's voices based on which, "norms" in behavior could be modeled, particularly for contemporary commercial music (CCM), such as musical theater (MT). The objective of this study was to assess if quantifia...