In the clinical setting, bleeding is a common manifestation of acute promyelocytic leukemia (APL), whereas thrombosis is relatively rare, especially as an initial symptom. Here, we report an unusual case of APL with acute myocardial infarction as the first manifestation and cerebral infarction as the relapse manifestation in a healthy young woman. This unique case emphasizes that a thrombotic e...

Objective: The incidence and range of rare hereditary bleeding diseases, as well the severity deficiency its many clinical presentations, were subjects our study. Study Design: Cross-sectional study Place Duration: Department Pathology, Northwest School Medicine Peshawar in duration from July, 2022 to December, 2022. Methods: Total 850 cases coagulation disorders presented this A thorough demog...

© 2002 Blackwell Science Ltd Superfi cial siderosis of the central nervous system (CNS) is a rare disorder, which is the consequence of chronic subarachnoid haemorrhage. Brain MR scan (Fig. 1) shows a characteristic marginal low T 2 -weighted signal of haemosiderin around the surface of the CNS, and has made antemortem diagnosis of this condition possible. Clinically, the cardinal features are ...

Inhibitors to factor V is a rare phenomenon with varied clinical presentation ranging from asymptomatic states life-threatening bleeds. They are known be associated exposure bovine thrombin, drugs, autoimmune diseases and malignancies. Establishing the diagnosis of FV inhibitors challenging presence lupus-like properties inhibitor can further complicate diagnosis. Here we document an unusual ca...

Alström syndrome is a rare autosomal recessive genetic disorder characterized by cone-rod dystrophy, hearing loss, childhood truncal obesity, insulin resistance and hyperinsulinemia, type 2 diabetes, hypertriglyceridemia, short stature in adulthood, cardiomyopathy, and progressive pulmonary, hepatic, and renal dysfunction. Alström syndrome is a very rare cause of liver cirrhosis. Postmortem bio...

Hemorrhage is one of the major complications cardiac surgery when using cardiopulmonary bypass (CPB). Despite all kinds medical and surgical treatment, post bleeding still a serious problem. Hypothermia, acidosis, hypovolemia, hypoperfusion lead to disruption coagulation process in severe trauma as well CPB. Hyperfibrinolysis (HF) life-threatening disorder patients. The incidence HF has been es...

Background: Cervical cavernous hemangioma is an extremely rare, benign lesions, and only a few cases are reported. Cervical cavernous Hemangiomas are characterized by an increase in the number of normal and abnormal veins. The majority of these lesions are superficial, often found in the head and neck area, but may also occur in the inner parts of the body. The occurrence of these lesions in th...